2022 Frontal Cortex Gordon Research Conference

摘要 前额叶皮层（PFC）参与认知和行为的各个方面，并在所有 精神疾病和物质使用障碍。在过去的四年里，PFC一直受到广泛的研究。 几十年在动物模型中研究PFC的兴趣已经以与人类研究相同的速度增长， 令人惊讶的是，没有既定的会议存在，重点是全氟化学品和汇集研究人员使用 不同的动物模型（非人灵长类动物、大鼠、小鼠）和各种实验方法（例如， 病变、药理学、解剖学、生理学、分子工具、计算模型）。一个新的戈登研究 会议（GRC）的额叶皮层已经成立，为有兴趣的研究人员提供一个论坛， PFC和相关的皮质区（例如，OFC）。GRC将于2022年8月在加利福尼亚州文图拉召开会议。是我们 希望能从NIH获得财政支持，以支持会议。国家卫生研究院的支持将使我们 以抵消我们邀请的演讲者和学员的出席费用，特别是来自代表性不足的群体。 我们提出以下目标：（1）围绕基本问题召集多元化的科学家队伍， 关于额叶皮层的研究会议将以恐惧/厌恶和奖励/食欲为主题 学习，据我们所知，在其他会议上没有一起讨论过， 神经解剖学，一个主题，是至关重要的临床前的研究结果，目前的研究在人群中。 (2)团结多元化的科学家队伍，围绕额叶皮层研究的新兴技术。面板将 讨论使用强大的工具，如光遗传学，化学遗传学和钙成像，以及它们如何 用于将小鼠和大鼠的研究与人类和非人类灵长类动物的研究结果联系起来。(3)到 促进女科学家、早期职业研究人员和代表性不足的研究人员的发展 在额叶皮层的研究中。我们将举办一个网络和辅导PowerHourTM专注于谈判 职业阶段。

Abstract The prefrontal cortex (PFC) is involved in all aspects of cognition and behavior and has established roles in all forms of mental illness and substance use disorders. The PFC has been studied intensely over the past four decades. Interest in studies of the PFC in animal models has grown at a pace equal to that of human studies on the PFC. Surprisingly, no established meetings exist that focus on the PFC and bring together researchers using different animal models (non-human primates, rats, mice) and a variety of experimental approaches (e.g., lesions, pharmacology, anatomy, physiology, molecular tools, computational models). A new Gordon Research Conference (GRC) on the Frontal Cortex has been established to provide a forum for researchers interested in the PFC and related cortical areas (e.g., OFC). The GRC will convene in Ventura, CA in August 2022. It is our hope that financial support can be obtained from the NIH to support the meeting. Support from NIH will allow us to offset the attendance costs of our invited speakers and trainees, especially from underrepresented groups. We propose the following Aims: (1) To convene a diverse scientist workforce around fundamental questions in research on the frontal cortex. The conference will feature panels on fear/aversive and reward/appetitive learning, which to our knowledge have not been discussed together at other meetings, and comparative neuroanatomy, a topic that is crucial for relating preclinical findings to current research in human populations. (2) To unite a diverse scientist workforce around emerging technologies in frontal cortex research. Panels will discuss the use of powerful tools such as optogenetics, chemogenetics, and calcium imaging and how they can be used to link studies in mice and rats to findings from studies in humans and non-human primates. (3) To promote the development of women scientists, early-career researchers, and under-represented investigators in frontal cortex research. We will host a networking and mentoring PowerHourTM focused on negotiation across career stages.