IBEX bone health screening on mammography systems

该项目将使用广泛可用的乳房X光摄影服务和筛查程序展示一种筛查骨质疏松症的独特方法。骨质疏松症是一种影响超过20%的50岁以上女性的疾病。这种疾病导致的脆性骨折对健康、死亡率和生活质量产生了毁灭性的影响，每年给全球医疗体系造成的损失超过4000亿美元。脆性骨折后：*40%的患者无法独立行走*60%的患者在至少一项基本的日常活动(如洗澡)中遇到困难*80%的患者被限制在其他活动中，如开车或购物*27%的患者首次进入疗养院尽管在确诊为骨质疏松症后有有效的药物治疗来降低骨折的风险，但没有常规的骨质疏松症筛查计划。IBEX骨健康(IBEX BH)软件产品的开发是为了从常规X光检查中识别骨骼健康，例如在骨折后进行其他检查。该项目将展示BH产品的可行性，它可以从使用现有乳房X光设备和服务收集的简单手腕X光以及乳腺癌筛查和治疗收集的乳房X光照片中提供骨健康测量。乳房X光检查提供了一个独特的机会来识别骨健康不良，因为处于骨质疏松症风险的女性是发展骨质疏松症的最高风险人群。配合她们的常规乳房筛查预约，通过在医院预约期间额外拍摄手腕X光片，为识别这一高危人群中的骨质疏松症提供了一个完美的机会。长期愿景是，所有女性在常规乳房X光检查的同时测量她们的骨密度，并接受治疗，以避免虚弱的骨折，并过上健康、积极的生活。

This project will demonstrate a unique method of screening for osteoporosis using widely available mammography services and screening programs.Osteoporosis is a condition that affects over 20% of women over the age of 50\. Fragility fractures resulting from the condition have a devastating impact on health, mortality and quality of life and cost the global healthcare system over $400bn per year. Following a fragility fracture:* 40% of patients are unable to walk independently* 60% encounter difficulties with at least one essential daily activity such as bathing* 80% are restricted in other activities such as driving or shopping* 27% enter a nursing home for the first timeDespite effective drug treatments being available to reduce risk of fractures following an osteoporosis diagnosis, there is no routine osteoporosis screening program. The condition is currently 80% underdiagnosed and women will typically suffer multiple fractures prior to a diagnosis.The IBEX Bone Health (IBEX BH) software product has been developed to opportunistically identify bone health from routine X-rays that have been taken for other investigations, for example following a fracture.This project will demonstrate the feasibility that the BH product can be extended to deliver a bone health measure from a simple wrist X-ray collected using existing mammography equipment and services alongside mammograms collected for breast cancer screening and treatment.Mammography provides a unique opportunity to identify poor bone health, since women at risk of osteoporosis are in the most at-risk demographic for developing osteoporosis. Aligning with their routine breast screening appointments offers a perfect opportunity to identify osteoporosis in this at-risk group by taking an additional wrist X-ray during their hospital appointment.The long-term vision is that all women have their bone density measured alongside their routine mammogram and are given the treatment to avoid debilitating fractures and live healthy, active lives.