IBEX bone health screening on mammography systems

乳腺 X 线摄影系统上的 IBEX 骨骼健康筛查

• 批准号: 10084028
• 金额: $ 18.08万
• 依托单位: IBEX INNOVATIONS LTD
• 依托单位国家: 英国
• 项目类别: Collaborative R&D
• 财政年份: 2023
• 资助国家: 英国
• 起止时间: 2023 至 无数据
• 项目状态: 未结题
• 来源: https://gtr.ukri.org/projects?ref=10084028
• 关键词: IBEX; bone; health; screening; mammography

This project will demonstrate a unique method of screening for osteoporosis using widely available mammography services and screening programs.Osteoporosis is a condition that affects over 20% of women over the age of 50\. Fragility fractures resulting from the condition have a devastating impact on health, mortality and quality of life and cost the global healthcare system over $400bn per year. Following a fragility fracture:* 40% of patients are unable to walk independently* 60% encounter difficulties with at least one essential daily activity such as bathing* 80% are restricted in other activities such as driving or shopping* 27% enter a nursing home for the first timeDespite effective drug treatments being available to reduce risk of fractures following an osteoporosis diagnosis, there is no routine osteoporosis screening program. The condition is currently 80% underdiagnosed and women will typically suffer multiple fractures prior to a diagnosis.The IBEX Bone Health (IBEX BH) software product has been developed to opportunistically identify bone health from routine X-rays that have been taken for other investigations, for example following a fracture.This project will demonstrate the feasibility that the BH product can be extended to deliver a bone health measure from a simple wrist X-ray collected using existing mammography equipment and services alongside mammograms collected for breast cancer screening and treatment.Mammography provides a unique opportunity to identify poor bone health, since women at risk of osteoporosis are in the most at-risk demographic for developing osteoporosis. Aligning with their routine breast screening appointments offers a perfect opportunity to identify osteoporosis in this at-risk group by taking an additional wrist X-ray during their hospital appointment.The long-term vision is that all women have their bone density measured alongside their routine mammogram and are given the treatment to avoid debilitating fractures and live healthy, active lives.

该项目将展示一种使用广泛可用的乳房X光检查服务和筛查计划筛查骨质疏松症的独特方法。骨质疏松症是一种影响超过20%的50岁以上女性的疾病。由这种疾病引起的脆性骨折对健康、死亡率和生活质量产生毁灭性影响，每年使全球医疗保健系统损失超过4000亿美元。脆性骨折后：* 40%的患者无法独立行走 * 60%的患者在至少一项基本日常活动（如洗澡）方面遇到困难 * 80%的患者在其他活动（如驾驶或购物）方面受到限制 * 27%的患者首次进入养老院尽管有有效的药物治疗可降低骨质疏松症诊断后骨折的风险，但没有常规的骨质疏松症筛查计划。目前80%的情况是诊断不足，妇女通常会遭受多处骨折之前的诊断。IBEX骨健康（IBEX BH）软件产品已经开发出来，以及时确定骨健康从常规X射线已采取的其他调查，例如骨折后。该项目将证明BH产品可以扩展到从骨折处提供骨骼健康测量的可行性。使用现有的乳房X光检查设备和服务收集的简单手腕X光检查，以及为乳腺癌筛查和治疗收集的乳房X光检查。乳房X光检查提供了一个独特的机会，以确定骨骼健康状况不佳，因为有骨质疏松症风险的妇女是最有可能患骨质疏松症的人群。与常规乳房筛查预约保持一致，为这一高危人群提供了一个绝佳的机会，通过在医院预约期间额外拍摄手腕X光片来识别骨质疏松症。长期愿景是所有女性在常规乳房X光检查的同时测量骨密度，并给予治疗，以避免使人衰弱的骨折，过上健康、积极的生活。