Data Coordinating and Operations Center for the ECHO IDeA States Pediatric Clinical Trials Network

项目总结 机构发展奖(IDEA)计划的资格是基于NIH历史上较低的水平 资金问题。就人口的城乡分布而言，理想状态与非理想状态不同 以及获得医疗服务的机会。与处于无想法状态的儿童相比，处于有想法状态的儿童更有可能 他们生活在农村地区，不太可能获得或接受医疗保健。自多中心儿科 临床试验网络集中在非理想状态的中心，儿童的机会有限 生活在理想状态中，参与临床研究活动。 ECHO IDEA国家临床试验网络(ISPCTN)成立于2016年，共有17名临床获奖者 站点和阿肯色大学医学数据协调和运营中心(DCOC) 阿肯色州小石城的科学(UAMS)。该网络的目标是制定和实施 该想法的临床研究表明，在回声优先领域：上呼吸道和下呼吸道疾病；肥胖症； 神经发育；产前、围产期和产后结局；积极的儿童健康；以及发展能力 在想法范围内进行临床试验研究。 这项建议是为了让UAMS继续担任ECHO ISPCTN的DCOC。的具体目标 数据协调和运营中心将 1)为ECHO想法提供科学、操作、行政和后勤基础设施支持 国家儿科临床试验网络(ISPCTN)，以促进开发、实施和 在ISPCTN内传播临床研究活动；以及 2)在理想状态下建设儿科临床研究能力，增强开展潜力 解决与处于IDEA状态的儿童相关的健康问题的临床试验。 我们将与ISPCTN网站、项目科学家和项目的临床研究人员合作 NIH ECHO办公室的官员和其他参与的NIH工作人员，以及合作的多中心临床试验 组织设计和实施研究，解决对农村和农村地区造成不成比例影响的健康问题 医疗服务不足的儿童。

PROJECT SUMMARY Eligibility for the Institutional Development Award (IDeA) program is based on historically low levels of NIH funding. IDeA states differ from non-IDeA states with respect to the rural/urban distributions of the population and access to medical care. Compared to children in non-IDeA states, children in IDeA states are more likely to live in rural areas and are less likely to have access to or receive medical care. Since multi-center pediatric clinical trial networks are concentrated in centers in non-IDeA states, there are limited opportunities for children living in IDeA states to participate in clinical research activities. The ECHO IDeA States Clinical Trials Network (ISPCTN) was established in 2016 with 17 clinical awardee sites and the Data Coordinating and Operations Center (DCOC) at the University of Arkansas for Medical Sciences (UAMS) in Little Rock, Arkansas. The objectives of the Network are to develop and implement clinical research in the IDeA states in the ECHO priority areas: upper and lower airway disease; obesity; neurodevelopment; pre-, peri-, and post-natal outcomes; and positive child health; and to develop capacity within the IDeA states to conduct clinical trial research. This proposal is for UAMS to continue to serve as the DCOC for the ECHO ISPCTN. The specific aims of the Data Coordination and Operations Center are to 1) Provide scientific, operational, administrative and logistical infrastructure support to the ECHO IDeA States Pediatric Clinical Trials Network (ISPCTN) to facilitate the development, implementation and dissemination of clinical research activities in the ISPCTN; and 2) Build pediatric clinical research capacity in the IDeA states to enhance the potential for conducting clinical trials that address health issues of relevance to children in IDeA states. We will work collaboratively with clinical investigators at the ISPCTN sites, Project Scientists and Project Officers at the NIH ECHO Office, and other participating NIH staff, and collaborating multicenter clinical trials groups to design and implement studies that will address health issues that disproportionately affect rural and medically underserved children.