Developmental Research Program

摘要：发展研究计划(DRP) MSCP孢子发育研究计划(DRP)提供种子资金以探索有前途的 黑色素瘤和其他皮肤癌的新研究，特别是目前没有从事研究的研究人员 这方面的研究。DRP将每年征集1-2次提案，并采用同行评议的评分 每年优先为2-3个提案提供资金的制度，最高可达75000美元/提案/年。DRP与孢子 联合董事、区域黑色素瘤联盟(RMC)代表和我们孢子内部的成员 咨询委员会(IAB)和外部咨询委员会(EAB)与 患者权益倡导者和判断项目可行性、翻译意义所需的任何其他专家 以及可能产生的整体影响。在最近的资助期间，MSCP孢子支持了9个DRP 基础研究、转化研究和临床研究的项目。DRP联席主任跟踪 成功申请，并为资助的调查人员指派导师，以确保他们获得任何所需的 这些服务来自MSCP孢子核心，并有效地整合到孢子计划中。 获奖者在资助一年后向MSCP孢子成员展示他们的研究成果 有资格获得第二年的支持。翻译方面的进步以及影响和创新将 在制定时确定DRP项目是否值得推广为全孢子项目 续约竞标。获奖者在准备拨款申请时，亦会在适当情况下获得通知。 在孢子机制之外，并给予所有孢子核心资源的访问权限，以帮助这一努力。DRP- 在最近的支持期内得到资助的研究获得了NIH R01、R21和P01的资助， 许多出版物和在地方、国家和国际会议/专题讨论会上的演讲有助于 在全球范围内提高MSC孢子能见度。

ABSTRACT: Developmental Research Program (DRP) The MSCP SPORE Developmental Research Program (DRP) provides seed funding to explore promising novel research in melanoma and other skin cancers, particularly by investigators not currently engaged in research in this area. The DRP will solicit proposals 1-2 times per year and applies a peer-reviewed scoring system to prioritize the funding of 2-3 proposals per year at up to $75K/proposal/year. The DRP and SPORE Co-Directors, Regional Melanoma Consortium (RMC) representatives, and members of our SPORE Internal Advisory Board (IAB) and External Advisory Board (EAB) participate in the review process, together with Patient Advocates and any additional experts necessary to judge project feasibility, translational significance and likely overall impact. During the most recent period of funding, the MSCP SPORE supported 9 DRP projects in basic, translational, and clinical research. The DRP Co-Directors track the progress of the successful applications and assign mentors to funded investigators to ensure that they obtain any needed services from the MSCP SPORE Cores, and that they are effectively integrated into the SPORE program. Awardees present their research results to the MSCP SPORE membership after one year of funding to become eligible for a second year of support. Progress toward translation as well as impact and innovation will determine whether DRP projects are found to merit promotion to full SPORE projects at the time of formulating a renewal bid. Awardees are also advised as appropriate in the preparation of grant applications for funding outside the SPORE mechanism and given access to all SPORE Core resources to aid in this endeavor. DRP- supported research over the most recent period of support resulted in funded NIH R01, R21 and P01 grants, numerous publications and presentations at local, national and international meetings/symposia that serve to enhance MSC SPORE visibility on a global level.