Career Enhancement

项目摘要/摘要 癌症研究的创新和进步需要致力于下一代的职业发展 一代癌症研究人员。因此，肯塔基大学的马基癌症中心(MCC)， 凭借每年45万美元的强劲机构投资和成员的奉献精神，建立了 全面的肿瘤学职业提升计划。在过去的资金周期中，该计划已经 为近570名K-12和本科生提供丰富的经验；广泛的研究培训 50名高中生、223名本科生和544名研究生/博士后研究人员；以及导师 给46名初级教员。值得注意的是，关键的教育活动解决了阿巴拉契亚农村地区的学术挑战。 肯塔基州和代表不足的少数族裔通过包括继续雨伞在内的4项赠款提供支持 国家癌症健康差异计划的研究经验和地理管理 学会补充剂。通过强化指导，促进所有学员的学术和专业发展 本科生、研究生和博士后一级的研究参与和/或正式研究培训 补充小学和高中教育战略。癌症生物学的正式课程已经 设立在本科生、硕士和博士前水平，为此提供学术背景 训练。此外，4个T32培训方案支持学员的癌症职业发展，包括2 由国家癌症研究所资助，其中1个专门为外科科学家提供资金。整体MCC 自2012年以来，培训和职业发展外部支持增加了52%，达到26笔赠款，总额为230万美元 (直接成本)2017年。通过正式的指导，早期教师受益于基于团队的指导 委员会，赠款写作学习大厅，临床试验训练营和协同指导通过 各种制度上的努力。这种指导产生了95项赠款(50项校外资助，45项校内资助) 以及11名临床科学家的发展，他们后来领导了31项临床试验。一套丰富的研讨会， 研讨会、会议和其他促进职业发展的活动有助于所有人的成功职业发展 从事癌症研究和临床实践的个人。所有当前和计划中的职业提升 活动利用MCC的4个研究计划中强大的研究实力，提供身临其境的 通过管道进行培训，并确保这些计划内的教员成功地发展为 独立的科学家。管理协调委员会的集体努力还利用强大的机构培训资源来 实现该计划的两个首要目标：引导凝聚力增长和协调跨学科 在整个MCC的教育和指导努力；并与校园内的其他努力相结合。穿过 CCSG的支持下，这一全面的计划将继续发展创新的课程和战略上的联系 为实习生和早期职业教师提供现代癌症职业机会的计划。此外， 这些努力将推动研究创新，改善所有肯塔基州人的生活。

PROJECT SUMMARY/ABSTRACT Innovation and progress in cancer research require dedication to the career development of the next generation of cancer researchers. Accordingly, the University of Kentucky’s Markey Cancer Center (MCC), with a robust annual institutional investment of $450,000 and the dedication of its members, established a comprehensive Oncology Career Enhancement Program. Over the past funding cycle, this program has provided enriching experiences for nearly 570 K-12 and undergraduate students; extensive research training for 50 high school students, 223 undergraduates and 544 graduate/postdoctoral researchers; and mentorship to 46 junior faculty. Notably, key education activities address the academic challenges of rural Appalachian Kentucky and underrepresented minorities through the support from 4 grants that include Continuing Umbrella of Research Experiences and Geographic Management of Health Disparities Program National Cancer Institute supplements. Academic and professional development of all trainees through intensive mentored research engagement and/or formal research training at the undergraduate, graduate and postdoctoral levels complement elementary and high school education strategies. Formal curricula in cancer biology have been established at the undergraduate, masters and pre-doctoral levels that provide the academic context for this training. Furthermore, 4 T32 training programs support cancer career development for trainees, including 2 funded by the National Cancer Institute, 1 of which is uniquely devoted to surgeon-scientists. Overall MCC training and career development extramural support has risen by 52% since 2012 to 26 grants totaling $2.3M (direct costs) in 2017. Early-career faculty benefit from team-based mentoring through formal mentoring committees, a Grant Writing Study Hall, the Clinical Trials Boot Camp and synergistic mentorship through various institutional efforts. This mentorship has resulted in 95 awarded grants (50 extramural, 45 intramural) and the development of 11 clinician scientists who went on to lead 31 clinical trials. A rich set of seminar, symposia, meetings and other career enhancement activities facilitate successful career development for all individuals engaged in cancer research and clinical practice. All current and proposed career enhancement activities leverage the robust research strengths within the MCC’s 4 Research Programs to provide immersive training across the pipeline and to ensure that faculty within these programs successfully develop as independent scientists. The MCC’s collective efforts also draw on strong institutional training resources to achieve 2 overarching goals of this program: to guide cohesive growth and coordinate transdisciplinary education and mentoring endeavors across the MCC; and to integrate with other efforts campus wide. Through CCSG support, this comprehensive program will continue to evolve innovative curricula and strategically linked initiatives that prepare trainees and early-career faculty for modern cancer career opportunities. Furthermore, these efforts will drive research innovation that will improve the lives of all Kentuckians.