Immunology (I) Core

免疫学（Immunology） 17名视觉科学家（持有13项符合条件的NEI R 01赠款）申请持续资助， 其人员将支持新设立的三个资源/服务核心和一个行政核心， 合并眼科、视觉和解剖科学系（原眼科 和解剖学/细胞生物学部门）。免疫学（I-Core）将由Ashok博士指导 Kumar说，他是R 01资助的研究人员，在免疫技术方面具有重要的专业知识。 与PI和研究助理一起， 韦恩州立大学及其附属机构的研究将通过以下方式得到加强 优先考虑NEI R 01资助的研究人员，他们的工作人员和学生（研究生和 在免疫学的许多方面。这个核心将确保视觉研究人员 持续使用流式细胞术/流式细胞仪中的现代仪器和方法， 其他免疫学测定，以促进他们的研究。I-core维持流式细胞术， 免疫印迹、ELISA和其他功能，使广泛的细胞分析成为可能。 研究领域的范围。I-core支持的实验将继续提供 先进的免疫学分析和专家咨询/培训，以视觉研究 社区，最大限度地利用和集中专门的免疫学研究工具，并启动和 鼓励创新的研究项目，解决新出现的眼科疾病问题。优先 对于NEI R 01资助的研究人员在韦恩州立大学（WSU）和其他附属 将提供机构。I-core还提供了一个支持性环境， NEI R 01资助的研究人员，临床医生和其他WSU及其附属机构之间的合作 研究人员开发和开展基础和转化视觉研究。I-core还 将以较低的优先级为新调查员和/或正在收集 初步数据将用于NEI R 01资助提交。

Project Summary (Immunology) Continuing funds are requested by 17 vision scientists (holding 13 eligible NEI R01 grants) and their personnel to support three resource/service cores and an administrative core in the newly merged Department of Ophthalmology, Visual and Anatomical Sciences (former Ophthalmology and Anatomy/Cell Biology Departments). The Immunology (I-Core) will be directed by Dr. Ashok Kumar, an R01-funded investigator with significant expertise in immunological techniques. Together with the PI, and a research assistant, the environment and capability to conduct vision research at Wayne State University and affiliated institutions will be enhanced through prioritization of the work of NEI R01 funded investigators, their staff and students (graduate and fellows) in numerous aspects of Immunology. This core will ensure vision researchers have ongoing access to contemporary instrumentation and approaches in flow cytometry/FACS and other immunological assays to facilitate their research. The I-core maintains flow cytometry, western blotting, ELISA, and other capabilities that enable advanced cell analyses for a wide range of research areas. The experimentation supported by I-core will continue to provide sophisticated immunological assays and expert consultation/training to the vision research community, maximize and centralize specialized immunology research tools, and initiate and stimulate innovative research projects addressing emerging questions of eye diseases. Priority for NEI R01 funded investigators at Wayne State University (WSU) and other affiliated institutions will be provided. The I-core also provide a supportive environment to foster collaboration among NEI R01 funded investigators, clinicians, and other WSU and affiliated investigators to develop and carry out basic and translational vision research. The I-core also will provide support, at reduced priority, for new investigators, and/or others who are collecting preliminary data to be used for NEI R01 grant submission.