Immunology (I) Core

项目摘要(免疫学) 17名视觉科学家申请继续资助(持有13项符合条件的NEI R01资助)和 他们的人员将支持三个资源/服务核心和一个行政核心 合并后的眼科、视觉和解剖科学系(原眼科 和解剖学/细胞生物学系)。免疫学(i-Core)将由阿肖克博士指导 库马尔是一名由R01资助的研究员，在免疫学技术方面拥有丰富的专业知识。 与PI和一名研究助理一起，环境和引导视觉的能力 韦恩州立大学及其附属机构的研究将通过 优先安排NEI R01资助的调查人员、他们的工作人员和学生(本科生和 研究员)在免疫学的许多方面。这一核心将确保视力研究人员有 持续获得流式细胞术/流式细胞仪和 其他免疫学检测，以方便他们的研究。I-core保持了流式细胞术， 免疫印迹、酶联免疫吸附试验和其他功能，使先进的细胞分析能够广泛 研究领域的范围。I-core支持的实验将继续提供 对视力研究进行复杂的免疫学检测和专家咨询/培训 社区，最大化和集中专门的免疫学研究工具，并发起和 鼓励创新研究项目，解决新出现的眼病问题。优先性 对于NEI R01资助的韦恩州立大学(WSU)和其他附属机构的调查人员 将提供机构。I-core还提供了一个支持性环境来促进 NEI R01资助的研究人员、临床医生和其他WSU及其附属机构之间的协作 研究人员开发和开展基础和翻译视觉研究。I-core还 将以较低的优先级为新调查人员和/或其他正在收集 初步数据将用于NEI R01赠款提交。

Project Summary (Immunology) Continuing funds are requested by 17 vision scientists (holding 13 eligible NEI R01 grants) and their personnel to support three resource/service cores and an administrative core in the newly merged Department of Ophthalmology, Visual and Anatomical Sciences (former Ophthalmology and Anatomy/Cell Biology Departments). The Immunology (I-Core) will be directed by Dr. Ashok Kumar, an R01-funded investigator with significant expertise in immunological techniques. Together with the PI, and a research assistant, the environment and capability to conduct vision research at Wayne State University and affiliated institutions will be enhanced through prioritization of the work of NEI R01 funded investigators, their staff and students (graduate and fellows) in numerous aspects of Immunology. This core will ensure vision researchers have ongoing access to contemporary instrumentation and approaches in flow cytometry/FACS and other immunological assays to facilitate their research. The I-core maintains flow cytometry, western blotting, ELISA, and other capabilities that enable advanced cell analyses for a wide range of research areas. The experimentation supported by I-core will continue to provide sophisticated immunological assays and expert consultation/training to the vision research community, maximize and centralize specialized immunology research tools, and initiate and stimulate innovative research projects addressing emerging questions of eye diseases. Priority for NEI R01 funded investigators at Wayne State University (WSU) and other affiliated institutions will be provided. The I-core also provide a supportive environment to foster collaboration among NEI R01 funded investigators, clinicians, and other WSU and affiliated investigators to develop and carry out basic and translational vision research. The I-core also will provide support, at reduced priority, for new investigators, and/or others who are collecting preliminary data to be used for NEI R01 grant submission.