Exploiting data for drug reprofiling

利用数据进行药物重新分析

• 批准号: 100922
• 金额: $ 42.1万
• 依托单位: CRESSET BIOMOLECULAR DISCOVERY LIMITED
• 依托单位国家: 英国
• 项目类别: Collaborative R&D
• 财政年份: 2011
• 资助国家: 英国
• 起止时间: 2011 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=100922
• 关键词: Exploiting; data; drug; reprofiling

The project aims to create a platform through which the partners are able to offer products and services to customers in the area of drug re-profiling or re-purposing. Re-profiling generally consists of looking for a new therapeutic application for an existing drug molecule, or stated another way, searching databases of known drug molecules to find compounds which have high similarity to a query structure of interest. Cresset and Biolauncher bring together skills in computational chemistry, large-scale textual informatics and semantic data integration to create a system which enables the provision of applications and services in such re-profiling exercises to life sciences customers.

该项目旨在创建一个平台，通过该平台，合作伙伴能够在药物重新分析或重新利用领域向客户提供产品和服务。重新分析通常包括寻找现有药物分子的新治疗应用，或者换句话说，搜索已知药物分子的数据库以找到与感兴趣的查询结构具有高度相似性的化合物。 Cresset 和 Biolauncher 汇集了计算化学、大规模文本信息学和语义数据集成方面的技能，创建了一个系统，能够在此类重新分析练习中向生命科学客户提供应用程序和服务。