An innovative urinary drainage system that could reduce NHS CAUTI treatment costs by 10% and increase quality-of-life for men suffering from chronic incontinence

％20创新％20泌尿％20引流％20系统％20％20可以％20减少％20NHS％20CAUTI％20治疗％20成本％20by％2010％％20和％20增加％20生活质量％20为％20男性％20痛苦％20来自％20慢性％20失禁

• 批准号: 10094849
• 金额: $ 23.3万
• 依托单位: INGENION MEDICAL LIMITED
• 依托单位国家: 英国
• 项目类别: Collaborative R&D
• 财政年份: 2024
• 资助国家: 英国
• 起止时间: 2024 至 无数据
• 项目状态: 未结题
• 来源: https://gtr.ukri.org/projects?ref=10094849
• 关键词: innovative; urinary; drainage; system; could

Ingenion is a UK-based medical device SME with a core project team of Edward Cappabianca (project lead), Susan Finch (project manager), James Barnett (design engineer), Tim Maloney (commercial director) and Zia Mursaleen (finance manager).Urinary incontinence impacts physical and emotional health, causing humiliation and social issues. Frequent catheterisation increases the risk of catheter-associated urinary tract infections (CAUTIs), which can be fatal and cost the NHS £567.6M/year. CAUTIs represent 17.2% of all Health-Care Associated Infections (HCAIs), and HCAIs have been estimated to cost the NHS between £1.6-£5B/year (Canadian-Journal-of -Infection-Control,Sep2020). Long-term catheter users experience an average of 2.7 CAUTIs per year (Coloplast, 2023), with a cost of £3,500 per incident. Around 90,000 people in the UK live with long-term catheters, with over 4B catheters used worldwide annually. Some people try to manage incontinence by drinking less water, but this has been shown to worsen apparently unrelated conditions, such as dementia.To solve this unmet need, Ingenion is developing a revolutionary indwelling urinary drainage system (_**cym**active_ SealSoft) that eliminates the need for external bags or tubes. The _**cym**active_ SealSoft device for incontinence will provide male patients with normal fill/void cycles without any inconvenience or risk of CAUTIs.This innovation will have a significant impact on patients suffering from MS, Parkinson's, spinal cord injuries and spina bifida. Not only will it improve their quality of life, but it will also help increase their life expectancy by allowing them to remain active. The unique selling points of this device are its leak-proof design and patented magnetic valve technology, which ensures greater confidence and a potential economic benefit from a reduction in CAUTI treatment costs for the NHS by 10% of the HCAIs related to CAUTIs could be as much as £57M/year.

Ingenion是一家总部位于英国的医疗器械SME，其核心项目团队包括Edward Cappabianca（项目负责人）、Susan Finch（项目经理）、James巴内特（设计工程师）、Tim Maloney（商务总监）和Zia Mursaleen（财务经理）。尿失禁会影响身体和情绪健康，造成羞辱和社会问题。频繁的导尿会增加导管相关尿路感染（catheter-associated urinary tract infection，CUTI）的风险，这可能是致命的，每年花费NHS 5.676亿英镑。急性呼吸道感染占所有卫生保健相关感染（HCAIs）的17.2%，据估计，HCAIs每年花费NHS 1.6- 50亿英镑（《健康控制杂志》，2020年9月）。长期导管使用者平均每年发生2.7例急性呼吸道感染（Coloplast，2023），每次事件的费用为3，500英镑。英国约有9万人长期使用导管，全球每年使用超过40亿根导管。有些人试图通过少喝水来控制尿失禁，但这已被证明会恶化明显无关的疾病，如痴呆症。为了解决这一未满足的需求，Ingenion正在开发一种革命性的留置尿引流系统（_**cym**active_ SealSoft），无需外部袋或管。用于失禁的_**cym**active_ SealSoft装置将为男性患者提供正常的充盈/排尿周期，而不会带来任何不便或发生尿道炎的风险。这一创新将对患有MS、帕金森氏症、脊髓损伤和脊柱裂的患者产生重大影响。它不仅会提高他们的生活质量，而且还将通过让他们保持活跃来帮助增加他们的预期寿命。该设备的独特卖点是其防漏设计和专利电磁阀技术，这确保了更大的信心和潜在的经济效益，因为NHS的HCAIs治疗成本降低了10%，与HCAIs相关的HCAIs可能高达5700万英镑/年。