Microscopy Imaging Center for Research through Observation (MICRO)

项目概要-核心B：通过观察进行研究的显微成像中心(MICRO) 通过观察进行研究的显微成像中心(MICRO)是 环境微生物与人类健康(ICEMHH)将提供全面的成像仪器 和夏威夷大学ʻI at MāNoa(UHM)的技术专长，以支持具有以下特征的研究 微生物及其相互之间、与宿主组织或与其环境的关系。微观意志 整合和增强现有的生物电子显微镜设备，该设备容纳了唯一的变速器 电子显微镜在状态下，和唯一的扫描电子显微镜在UHM支持生物和 生物医学研究。微芯将提供以下服务：仪器、培训和服务 扫描和透射式电子显微镜、荧光和共聚焦显微镜和激光 显微解剖和光学镊子。科布雷支持的一个主要目标将是使设备现代化和 向用户介绍新技术，特别是快速变化的荧光成像技术，以帮助 微生物及其微生物群的研究。微核心向新生命科学的重新定位 计划于2019年完工的大楼将提供更大的定制设计空间，以增强其 研究和培训活动。微核将向UHM园区的研究人员提供，以 其他当地研究和教育机构，以及来访的科学家。微芯将是有利的 Impact Cobre调查人员及其附属机构通过提供必要的基础设施和专业知识 他们的研究和促进合作，将积极影响初级调查人员的职业生涯和更多 老牌调查员。微核心将支持ICEMHH的发展，并(I)使其具有可见性 通过其研究和培训努力，(2)与先进的仪器和技术并驾齐驱 (3)促进推广活动，以确定夏威夷的微生物群的特征。

Project Summary – CORE B: Microscopy Imaging Center for Research through Observation (MICRO) The Microscopy Imaging Center for Research through Observation (MICRO) Core of the Integrative Center for Environmental Microbiomes and Human Health (ICEMHH) will provide comprehensive imaging instrumentation and technical expertise at the University of Hawaiʻi at Mānoa (UHM) to support research that characterizes microorganisms and their relationship to each other, to host tissues or to their environment. The MICRO will incorporate and enhance the existing Biological Electron Microscope Facility that houses the only transmission electron microscope in the state, and the only scanning electron microscope at UHM supporting biological and biomedical research. The MICRO Core will provide the following: instrumentation, training and services for scanning and transmission electron microscopy, epifluorescent and confocal microscopy and laser microdissection and optical tweezers. A major goal of the COBRE support will be to modernize equipment and introduce users to new techniques, particularly rapidly changing fluorescent-imaging technologies, to assist in studies of microorganisms and their microbiomes. Relocation of the MICRO Core to a new Life Sciences Building, scheduled for completion in 2019, will provide a larger, custom-designed space for enhancing its research and training activities. The MICRO Core will be available to researchers across the UHM campus, to other local research and educational institutions, and to visiting scientists. The MICRO Core will favorably impact COBRE investigators and their affiliates by providing essential infrastructure and expertise to advance their research and foster collaborations that will positively impact the careers of junior investigators and more established investigators. The MICRO Core will support the growth of the ICEMHH, and (i) bring it visibility through its research and training efforts, (ii) staying abreast of advancing instrumentation and technologies in microscopy, and (iii) facilitation of outreach activities to characterize Hawaii's microbiomes.