Safe and Sustainable by Design framework for the next generation of Chemicals and Materials

SSbD 4ChEM汇集了来自行业，政府，学术界和民间社会的利益相关者，通过3个案例研究的演示，开发和推广安全和可持续产品和工艺设计的最佳实践。SSbD 4Chem旨在通过制定一个全面的安全和可持续设计（SSbD）框架来实现欧盟在数字化、赋能和新兴技术、行业和价值链方面的战略目标，该框架使用新的基于科学的方法来识别和解决潜在的危害和风险，并使用创新技术来支持更安全和更可持续的产品和工艺的设计。SSbD 4Chem目标包括：1）SSbD框架，以促进下一代化学品和材料的开发，这些化学品和材料适用于汽车价值链中的可再生复合材料，用于纺织品和纤维素纳米纤维的无PFAS涂层，作为化妆品中的添加剂，以取代塑料微珠，2）开发有效的危害筛选工具，用于下一代化学品/材料/产品的替代评估，结合计算机工具和多标准分析，3）先进的探索性事前LCA方法，由分子和数据驱动的建模支持，以填补（新）材料和化学品的数据空白，4）整合化学/（纳米）材料表征方法，以评估产品的环境安全性，量化排放，以支持职业和消费者安全限制，5）开发替代体外模型，作为适当暴露情景的新方法学的一部分，6）协调和验证分析和毒理学方法，以向监管和标准化机构提出建议，促进新标准的制定，并促进SSbD 4Chem项目结果的市场接受，以及7）通过利益相关者的参与增强SSbD 4Chem的整体影响，培训、传播和开发，并推动工业创新。

SSbD4ChEM brings together stakeholders from industry, government, academia, and civil society to develop and promote best practices for safe and sustainable product and process design, through demonstration in 3 case studies. SSbD4CheM aims to meet the EU's strategic objectives for digital, enabling, and emerging technologies, sectors, and value chains by developing a comprehensive Safe and Sustainable by Design (SSbD) framework that uses new science-based approaches to identify and address potential hazards and risks, and innovative technologies to support the design of safer and more sustainable products and processes. SSbD4CheM objectives include: 1) SSbD framework to facilitate development of the next generation of chemicals and materials applicable to renewable composites in automotive value chain, PFAS-free coatings for textile and cellulose nanofibers as additive in cosmetics to replace plastic microbeads, 2) Development of efficient hazard screening tools for alternative assessment of next generation chemicals/materials/products combining in silico tools and multicriteria analysis, 3) Advanced explorative ex-ante LCA method supported by molecular and data-driven modelling to fill data gaps for (novel) materials and chemicals, 4) Integration of chemical/(nano-)material characterization methods to assess products’ environmental safety, quantify emissions to support occupational and consumer safety limits, 5) Development of alternative, in vitro models, as part of New Approach Methodologies for adequate exposure scenarios, 6) Harmonization and validation of analytical and toxicological methods for proposition to regulatory and standardization bodies to contribute to the development of new standards and facilitate market acceptance of SSbD4CheM project results, and 7) Enhance overall SSbD4CheM impact through stakeholder engagement, training, dissemination and exploitation and drive industrial innovation.