An Integrated Life-course Approach for Person-centred Solutions and Care for Ageing with Multi-morbidity in the European Regions - STAGE; Stay Healthy Through Ageing

欧洲地区以人为本的解决方案和针对多种疾病的老龄化护理的综合生命全程方法 - STAGE；

• 批准号: 10112787
• 金额: $ 70.34万
• 依托单位: BETA TECHNOLOGY LIMITED
• 依托单位国家: 英国
• 项目类别: EU-Funded
• 财政年份: 2024
• 资助国家: 英国
• 起止时间: 2024 至 无数据
• 项目状态: 未结题
• 来源: https://gtr.ukri.org/projects?ref=10112787
• 关键词: Integrated; Life; course; Approach; Person

STAGE aims to demonstrate the importance and feasibility of a life-course approach to prevent accelerated ageing, as defined by the accumulation of multi-morbidity, and to integrate knowledge into transferable person-centred solutions for early diagnosis and screening, treatment and long-term management of multi-morbidity. To achieve this, STAGE is proposing a life-course approach to better understand ageing with multi-morbidity, providing evidence-based solutions to support the transformation of healthcare to address the profound health and demographic challenges ahead. The approach capitalises on European collaborations of longitudinal cohorts and biobanks spanning the entire life-course, actioning exposome and disease networks trajectory analysis, as well as, the biology of ageing, to explore how a person develops ageing with multi-morbidity. The project objectives integrate an ethical, social, historical, and infrastructural framework; environmental, epidemiological and biological life-course approaches; artificial intelligence powered integrated person centred solutions and applications; cohort-based clinical studies; and a FAIR (findable, accessible, interoperable and reusable) life-course health and geospatial data portal with robust management, dissemination, engagement and exploitation activities. STAGE's evidence based methods will translate into a person-centred prevention and care intervention in longitudinal cohorts in Finland and Germany, co designed with citizens, patients, healthcare providers, SMEs, and policymakers. It will also embed social sciences and humanities and engage stakeholders to develop a neighbourhood healthy ageing index, person-centred predictions of multi-morbidity, and healthcare and policy recommendations. Ultimately, STAGE will create solutions for agile, high-quality, person-centred health and care services that are life-course and gender sensitive, needs-based, and designed to enhance resilience and participation.

STAGE的目的是证明一种生命过程方法的重要性和可行性，以防止由多种疾病积累所定义的加速衰老，并将知识纳入可转移的以人为中心的解决方案，以早期诊断和筛查、治疗和长期管理多种疾病。为实现这一目标，STAGE提出了一种生命历程方法，以更好地了解多发病老龄化，提供基于证据的解决方案，支持医疗保健改革，以应对未来深刻的健康和人口挑战。该方法利用欧洲纵向队列和跨越整个生命历程的生物库的合作，行动暴露和疾病网络轨迹分析，以及衰老生物学，探索一个人如何在多种疾病的情况下发展衰老。项目目标整合了道德、社会、历史和基础设施框架；环境、流行病学和生物生命历程方法；人工智能驱动的以人为本的集成解决方案和应用；基于队列的临床研究；一个公平（可查找、可获取、可互操作和可重复使用）的生命周期健康和地理空间数据门户，具有强有力的管理、传播、参与和利用活动。STAGE基于证据的方法将在芬兰和德国的纵向队列中转化为以人为中心的预防和护理干预，与公民、患者、医疗保健提供者、中小企业和政策制定者共同设计。它还将纳入社会科学和人文科学，并使利益攸关方参与制定社区健康老龄化指数，以人为中心的多发病预测，以及医疗保健和政策建议。最终，阶段性阶段将为灵活、高质量、以人为本的保健和护理服务提供解决方案，这些服务对生命过程和性别问题敏感，以需求为基础，旨在增强复原力和参与。