Liquid Helium Recovery System to Improve Shared Chemistry Instrumentation Core

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The University of Hawaii at Hilo (UH Hilo) is an Institution of Emerging Excellence in pharmaceutical and environmental health sciences with a Shared Chemistry Instrument (SCI) core that supports biomedical research conducted by a diverse team of investigators across campus with expertise in medicinal, natural products, organic, environmental, photo, and pharmaceutical chemistry. Given that the NMR instruments are critical to the productivity of these researchers and that helium is a non-renewable resource with steadily increasing costs, the addition of an advanced liquid helium recovery and liquefaction system will enable major improvements in operational efficiencies, strategically promote using shared resources, and strengthen our active biomedical research at the college of pharmacy and across UH Hilo. The long-term objective of this proposal is to enhance the sustainability and impact of the SCI core. This modernization project will advance research-related activities of the SCI core to support biomedical research and enhance the efficacy of the core’s operation through achievement of two aims: Aim 1. Reduce SCI core operating costs through the purchase and installation of a modern helium recovery system. Aim 2. Expand access to the core by offering lower NMR user fees and helium liquefaction services.