Mid-Atlantic praGmatic NETwork for Inclusive Clinical trials in emergency care (MAGNETIC)

我们将建立一个包容和高效的研究临床中心，在7个试验点的急诊科开展务实的临床试验。我们的临床中心有机会获得不同人群的个人心脏和神经紧急医疗条件和一大批有才华的专家。我们利用我们相当大的机构研究资源、先前的关系和先前的NIH投资。我们将为CCC、DCC、管理和运营委员会以及个别试验委员会提供创新的试验管理解决方案。我们聘请了来自不同专业领域的一些最重要的专家加入我们的联合调查员团队。杜克大学的合作文化将为这一事业带来基础科学、转化和临床研究人员。我们招募了7个高容量的学术卫生系统作为Spoke站点，以最大限度地增加我们参与任何拟议试验的机会。这7个系统的地理位置都很近，我们之前与所有Spoke pi和联合调查员都有过合作。这将导致显著的站点启动效率。

We will create an inclusive and efficient research Clinical Center to conduct pragmatic clinical trials in emergency departments across 7 spoke sites. Our Clinical Center has access to a diverse population of individuals with cardiac and neurologic emergency medical conditions and a host of talented experts. We leverage our considerable institutional research resources, prior relationships, and prior NIH investment. We will bring innovative trial management solutions to the CCC, DCC, the Management and Operations committees, and individual Trial Committees. We have engaged some of the foremost experts from a diverse range of specialties to our Co-Investigator team. Duke's collaborative culture will bring basic science, translational, and clinical researchers to bear on this enterprise. We enlisted 7 high-volume academic health systems as Spoke sites to maximize our opportunities to participate in any proposed trial. All 7 systems are in close geographic proximity and we have previously worked with all Spoke PIs and Co-Investigators. This should lead to significant site-startup efficiency.