Mid-Atlantic praGmatic NETwork for Inclusive Clinical trials in emergency care (MAGNETIC)

中大西洋紧急护理包容性临床试验实用网络 (MAGNETIC)

• 批准号: 10552216
• 负责人: Michael L. James
• 金额: $ 45.42万
• 依托单位: DUKE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-02-01 至 2028-08-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10552216
• 关键词: Academic Medical Centers; Accident and Emergency department; Basic Science; Cardiac; Clinical; Clinical Trials; Communities; Emergency Care; Environment; Geography; Health system; Healthcare; Hospitals; Individual; Institution; Investments; Medical emergency; Neurological emergencies; Population Heterogeneity; Pragmatic clinical trial; Research; Research Personnel; Resources; Site; System; Talents; United States National Institutes of Health; Work; clinical center; innovation; medical specialties; operation; participant enrollment; tertiary care

We will create an inclusive and efficient research Clinical Center to conduct pragmatic clinical trials in emergency departments across 7 spoke sites. Our Clinical Center has access to a diverse population of individuals with cardiac and neurologic emergency medical conditions and a host of talented experts. We leverage our considerable institutional research resources, prior relationships, and prior NIH investment. We will bring innovative trial management solutions to the CCC, DCC, the Management and Operations committees, and individual Trial Committees. We have engaged some of the foremost experts from a diverse range of specialties to our Co-Investigator team. Duke's collaborative culture will bring basic science, translational, and clinical researchers to bear on this enterprise. We enlisted 7 high-volume academic health systems as Spoke sites to maximize our opportunities to participate in any proposed trial. All 7 systems are in close geographic proximity and we have previously worked with all Spoke PIs and Co-Investigators. This should lead to significant site-startup efficiency.

我们将创建一个包容、高效的研究临床中心，在 7 个辐射点的急诊科开展务实的临床试验。我们的临床中心可以接触到患有心脏病和神经系统紧急医疗状况的不同人群以及众多才华横溢的专家。我们利用我们大量的机构研究资源、先前的关系和 NIH 的先前投资。我们将为 CCC、DCC、管理和运营委员会以及各个试验委员会带来创新的试验管理解决方案。我们聘请了一些来自不同专业领域的顶尖专家加入我们的联合研究者团队。杜克大学的合作文化将让基础科学、转化和临床研究人员为这个事业发挥作用。我们招募了 7 个大容量学术卫生系统作为 Spoke 站点，以最大限度地增加我们参与任何拟议试验的机会。所有 7 个系统地理位置都很接近，我们之前曾与所有 Spoke PI 和联合调查员合作过。这应该会显着提高站点启动效率。