HIP FRACTURE AND STROKE TRENDS IN AN AGING POPULATION

老年人群中髋部骨折和中风的趋势

• 批准号: 2053624
• 负责人: WILLIAM H BARKER
• 金额: $ 33.84万
• 依托单位: KAISER FOUNDATION RESEARCH INSTITUTE
• 依托单位国家: 美国
• 财政年份: 1994
• 资助国家: 美国
• 起止时间: 1994-09-01 至 1997-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2053624
• 关键词: aging; cardiovascular disorder epidemiology; chronic disease /disorder; epidemiology; female; functional ability; hip fractures; human data; human morbidity; human mortality; human old age (65+); human subject; longitudinal human study; male; stroke

This proposal constitutes part of a growing body of research designed to understand trends in mortality, morbidity, survival, and disability levels for selected major diseases among older persons, and implications of the findings for health care utilization. Specifically, the proposal consists of a retrospective study of successive cohorts of older members of a well- defined and well-documented elderly population for the following purposes: Defining and explaining the trends in hip fracture incidence, mortality, long-term survival, and functional outcomes among males and females during the 25 year period 1967-1992. Defining and explaining changes in stroke incidence, mortality, survival, and severity between 1981 and 1992, as an extension of a previous study of stroke trends. The study population consists of four successive period cohorts of elderly people identified for the following five-year periods: 1967-71,1974- 78,1981-85,1988-92. The first three cohorts 'have already been defined, while the fourth will be defined as part of the current proposal. Hypotheses are as follows: A Hip Fracture That during the period 1967-1992: Age-specific incidence of hip fracture among persons > 65 years of age has increased. There has been an increase in short- and long-term hip fracture survival. There has been an increase in post-fracture functional independence among survivors of acute hip fracture. Stroke That during the period 1981-92: Age-specific incidence of stroke among persons > 65 years of age has increased. Clinical severity and case fatality of stroke has decreased. Increased incidence and decreased severity are attributable in part to change in the natural history of disease and in part to ascertainment of milder cases using newer imaging technology.

这项建议是越来越多的研究的一部分， 了解死亡率、发病率、存活率和残疾水平的趋势 某些老年人主要疾病的影响， 卫生保健利用率的调查结果。具体而言，该提案包括 一项对一个井的老年成员的连续队列的回顾性研究， 为以下目的，确定和记录良好的老年人口： 定义和解释髋部骨折发病率的趋势， 男性的死亡率、长期生存率和功能结局， 1967-1992年25年间的女性。 定义和解释中风发病率、死亡率、 1981年至1992年期间的生存率和严重程度， 中风趋势的研究。 研究人群由四个连续的老年人队列组成。 1967- 1971年、1974- 78,1981-85,1988-92.前三个队列的定义已经确定， 而第四个将被定义为当前提案的一部分。 假设如下： 在1967年至1992年期间发生的髋关节骨折： 人群中髋部骨折的特定年龄发病率> 65岁的人增加了。 在短期和长期的髋关节置换中， 骨折存活率 骨折后的功能性骨折 急性髋部骨折幸存者的独立性。 在一九八一至九二年期间： 65岁以上人群中脑卒中的特定发病率 年龄增加了。 中风的临床严重程度和病死率下降。 发病率增加和严重程度降低可归因于 一部分原因是疾病的自然史发生了变化， 使用更新的成像技术确定较轻的病例。