Automated characterisaton of human gene regulatory networks for precision medicine
Automated characterisaton of human gene regulatory networks for precision medicine
批准号:
102982
负责人:
金额:
$8.77万
依托单位:
依托单位国家:
英国
项目类别:
Feasibility Studies
财政年份:
2017
资助国家:
英国
项目状态:
已结题
起止时间:
2017 至 --
中文摘要
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英文摘要
Understanding gene regulatory networks (GRNs) is critical to our understanding of cellular function and disease. However, the current experimental paradigm of using cell-based assays for GRN characterisation is slow, laborious and costly, resulting in limited data output of low quantitative resolution. In this project, SkyLab Bio confronts these problems using a different approach. We will harness state-of-the-art biological systems, automation and computation to create a high-throughput, rapid, robust and highly reproducible human in vitro GRN prototyping service. This will provide a reliable solution to determining causality in gene regulation, allowing for a more quantitative, unparalleled insight into GRN organisation.
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