TUMOR EVALUATION BY ENDOLUMINAL 2D AND 3D ULTRASOUND

这个项目的目的是评估2维的能力 (2D)和3D(3D)腔内超声导致将其用于 诊断和分期各种肿瘤。这项研究计划包括 三个要素：1)二维和三维腔内超声性能研究 使用体模；2)使用动物评价三维超声成像 肿瘤模型和各种3D重建模型的验证； 3)人体肿瘤的临床二维和三维验证。该项目将专注于 三种肿瘤：尿路上皮、子宫内膜和食道。这个 候选人刘继斌博士对评估 使用以下动物模型在身体不同区域发现肿瘤 兔VX2肿瘤和土拨鼠肝癌。他在动物方面的专长 自从他加入这个组织以来的四年时间里，实验一直在发展。 诊断超声科。这位候选人已经有了广泛的 在各种动物中使用微型传感器的经验 过去四年的模特和病人。候选人将接受 计算机科学、生物统计学、物理学和工程学课程 扩展他的知识基础。候选人的赞助商巴里·B·戈德堡 医学博士，诊断超声科主任和杰斐逊 超声波研究与教育研究所，已有三十多家 在超声波方面有多年的经验，并在许多领域担任过研究人员 资助金。这位候选人的其他导师包括一位超声波物理学家， 一名计算机科学家和一名生物统计学家。有重要的研究 可用的材料和空间。这包括超声波物理学 实验室，配备超声波和X射线设备的动物设施，以及 一个装有现有3D重建程序的计算机中心。

The aim of this project is to evaluate the capabilities of 2-dimensional (2D) and 3-dimensional (3D) endoluminal ultrasound leading to its use to diagnose and stage a variety of tumors. This research plan comprises three elements: 1) 2D and 3D endoluminal ultrasound performance studies using phantoms; 2) evaluation of 3D ultrasound imaging using an animal tumor model and validation of a variety of 3D reconstructional models; 3) clinical 2D and 3D Validation in human tumors. The project will focus on three tumors: uroepithelial, endometrial and esophageal. The candidate, Dr. Ji-Bin Liu, has particular interest in evaluation of tumors in a variety of areas of the body using such animal models as rabbit VX2 tumors and woodchuck hepatomas. His expertise in animal experimentation has evolved over the four years since he joined the Division of Diagnostic Ultrasound. The candidate has had extensive experience working with miniature transducers in a variety of animal models and patients over the past four years. The candidate will take courses in computer science, biostatistics, physics and engineering to extend his knowledge base. The candidate's sponsor, Barry B. Goldberg, M.D., Director of the Division of Diagnostic Ultrasound and the Jefferson Ultrasound Research and Education Institute, has had more than thirty years of experience in ultrasound and has been an investigator on many grants. The candidate's other mentors include an ultrasound physicist, a computer scientist and a biostatistician. There is significant research material and space available. This includes an ultrasound physics laboratory, an animal facility with ultrasound and x-ray equipment and a computer center with existing 3D reconstruction programs.