CHEMOTHERAPY INDUCED IMMUNE-MEDIATED TUMOR ERADICATION

化疗诱导免疫介导的肿瘤根除

• 批准号: 2095904
• 负责人: MARGALIT B MOKYR
• 金额: $ 16.32万
• 依托单位: UNIVERSITY OF ILLINOIS AT CHICAGO
• 依托单位国家: 美国
• 财政年份: 1992
• 资助国家: 美国
• 起止时间: 1992-05-15 至 1996-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2095904
• 关键词: CHEMOTHERAPY; INDUCED; IMMUNE; MEDIATED; TUMOR

项目成果

Low-dose-melphalan-induced up-regulation of type-1 cytokine expression in the s.c. tumor nodule of MOPC-315 tumor bearers and the role of interferon gamma in the therapeutic outcome.

低剂量马法兰诱导皮下 1 型细胞因子表达上调

• DOI: 10.1007/bf01526556
• 发表时间: 1995
• 期刊: Cancer immunology, immunotherapy : CII
• 作者: Gorelik,L;Mokyr,MB
• 通讯作者: Mokyr,MB

Cooperation between staphylococcal enterotoxin B and low dose melphalan in the cure of mice bearing a large MOPC-315 tumor and extensive metastases.

葡萄球菌肠毒素 B 和低剂量美法仑联合治疗携带大 MOPC-315 肿瘤和广泛转移的小鼠。

• 发表时间: 1994
• 期刊: Journal of immunology (Baltimore, Md. : 1950)
• 作者: Rubin,M;Bluestone,JA;Newell,KA;Prokhorova,A;Mokyr,MB
• 通讯作者: Mokyr,MB

Transforming growth factor-beta-mediated down-regulation of antitumor cytotoxicity of spleen cells from MOPC-315 tumor-bearing mice engaged in tumor eradication following low-dose melphalan therapy.

转化生长因子-β 介导的 MOPC-315 荷瘤小鼠脾细胞抗肿瘤细胞毒性的下调，这些小鼠在低剂量美法仑治疗后进行肿瘤根除。

• DOI: 10.1007/bf01533512
• 发表时间: 1994
• 期刊: Cancer immunology, immunotherapy : CII
• 作者: Weiskirch,LM;Bar-Dagan,Y;Mokyr,MB
• 通讯作者: Mokyr,MB

Involvement of TCR-V beta 8.3+ cells in the cure of mice bearing a large MOPC-315 tumor by low dose melphalan.

TCR-V beta 8.3 细胞参与低剂量马法兰治疗患有大 MOPC-315 肿瘤的小鼠。

• 发表时间: 1993
• 期刊: Journal of immunology (Baltimore, Md. : 1950)
• 作者: Mokyr,MB;Rubin,M;Newell,KA;Prokhorova,A;Bluestone,JA
• 通讯作者: Bluestone,JA

Importance of TNF production for the curative effectiveness of low dose melphalan therapy for mice bearing a large MOPC-315 tumor.

TNF 的产生对于低剂量美法仑治疗携带大 MOPC-315 肿瘤的小鼠的疗效的重要性。

• 发表时间: 1995
• 期刊: Journal of immunology (Baltimore, Md. : 1950)
• 作者: Gorelik,L;Rubin,M;Prokhorova,A;Mokyr,MB
• 通讯作者: Mokyr,MB