CORE--HISTOLOGY, IMMUNOHISTOCHEMISTRY, IN SITU HYBRIDIZATION

核心--组织学、免疫组织化学、原位杂交

• 批准号: 3735247
• 负责人: VERONICA ROBERTS
• 金额: --
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN DIEGO
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/3735247
• 关键词: animal tissue; biomedical equipment resource; biomedical facility; histology; human tissue; immunocytochemistry; in situ hybridization; tissue /cell preparation

The localization of proteins and MRNAS in animal and human cells and tissues are crucial to our understanding the neuroendocrine and metabolic regulation of the menstrual cycle. Five of the six Units in the Center will examine protein and MRNA distributions to answer key questions regarding hormonal expression, regulation, and site of action. Core C, the histology, immunohistochemistry, and in situ hybridization Core, directed by Dr. Roberts, will centralize these functions in a well equipped laboratory run by experienced personnel. This will optimize and standardize the quality of the results, eliminate the development and perfection of these techniques by the individual Units, and greatly cut material and personnel expenses.

蛋白质和MRNAS在动物和人类细胞中的定位， 组织对于我们理解神经内分泌和代谢 调节月经周期。 中心六个单元中的五个 将研究蛋白质和mRNA的分布，以回答关键问题 关于激素的表达、调节和作用部位。 核心C， 组织学、免疫组织化学和原位杂交核心，定向 由罗伯茨博士，将集中这些功能在一个装备精良的 实验室由经验丰富的人员管理。 这将优化和 规范成果质量，淘汰发展， 这些技术的完善，由个别单位，并大大削减 材料和人员费用。