MAPPING THE IGF II BINDING SITE OF THE IGF II RECEPTOR

绘制 IGF II 受体的 IGF II 结合位点图谱

• 批准号: 2143619
• 负责人: RICHARD G. MACDONALD
• 金额: $ 2.61万
• 依托单位: UNIVERSITY OF NEBRASKA MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 1996
• 资助国家: 美国
• 起止时间: 1996-02-25 至 1996-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2143619
• 关键词: MAPPING; IGF; II; BINDING; SITE

项目成果

An insulin-like growth factor II (IGF-II) affinity-enhancing domain localized within extracytoplasmic repeat 13 of the IGF-II/mannose 6-phosphate receptor.

胰岛素样生长因子 II (IGF-II) 亲和力增强结构域，位于 IGF-II/甘露糖 6-磷酸受体的胞质外重复序列 13 内。

• DOI: 10.1210/mend.12.11.0192
• 发表时间: 1998
• 期刊: Molecular endocrinology (Baltimore, Md.)
• 作者: Devi,GR;Byrd,JC;Slentz,DH;MacDonald,RG
• 通讯作者: MacDonald,RG

Localization of the insulin-like growth factor II (IGF-II) binding/cross-linking site of the IGF-II/mannose 6-phosphate receptor to extracellular repeats 10-11.

IGF-II/甘露糖 6-磷酸受体的胰岛素样生长因子 II (IGF-II) 结合/交联位点定位于细胞外重复序列 10-11。

• 发表时间: 1994
• 期刊: The Journal of biological chemistry
• 作者: Garmroudi,F;MacDonald,RG
• 通讯作者: MacDonald,RG

Truncated forms of the insulin-like growth factor II (IGF-II)/mannose 6-phosphate receptor encompassing the IGF-II binding site: characterization of a point mutation that abolishes IGF-II binding.

• DOI: 10.1210/mend.10.6.8776724
• 发表时间: 1996-06
• 期刊: Molecular endocrinology
• 作者: Farideh Garmroudi;G. Devi;D. Slentz;B. Schaffer;R. Macdonald