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DRUG ABUSE AND PSYCHIATRIC CO-MORBIDITY

DRUG ABUSE AND PSYCHIATRIC CO-MORBIDITY
药物滥用和精神共病
批准号：
3088828
负责人：
DOUGLAS MICHAEL ZIEDONIS
金额：
$10.89万
依托单位：
YALE UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
1993
资助国家：
美国
项目状态：
已结题
起止时间：
1993-07-01 至 1998-06-30
来源：
https://reporter.nih.gov/project-details/3088828
关键词：
antipsychotic agents crack cocaine desipramine drug abuse drug abuse chemotherapy gender difference health care service evaluation human morbidity human subject human therapy evaluation mental disorder chemotherapy mental disorders mental health epidemiology paranoid schizophrenia

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中文摘要
翻译
SDAC研究计划分为两部分：1.研究计划；评估研究。我们计划
英文摘要
The SDAC research plan has two parts: 1. Assessment Study. We plan to study the prevalence and patterns of drug abuse in 360 chronic mentally ill (CMI) individuals by using a comprehensive drug abuse assessment battery. 180 of the CMI are already enrolled in a 7 year prospective psychiatric study which has collected a wealth of data, but not on drug abuse. The other 180 CMI are seeking substance abuse treatment. This study will describe the association of drug abuse and sociodemographics, psychopathology, family history, and clinical course. 2. Treatment Study. We plan to assess the efficacy of innovative treatment approaches for schizophrenic cocaine abusers, including a double blind pharmacotherapy trial comparing adjunctive desipramine versus placebo in the context of a comprehensive treatment program.
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