E-Breather, Electronic Inhaled Drug Delivery Device

E-Breather，电子吸入药物输送装置

• 批准号: 133497
• 金额: $ 17.8万
• 依托单位: E-BREATHE LTD.
• 依托单位国家: 英国
• 项目类别: Feasibility Studies
• 财政年份: 2018
• 资助国家: 英国
• 起止时间: 2018 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=133497
• 关键词: Breather; Electronic; Inhaled; Drug; Delivery

"E-breather: Electronic inhalation device for drug delivery that improves effectiveness of delivery and patient compliance for respiratory conditions.The development of an inhalation device aims to reduce healthcare costs and enhance patient outcomes via a combination of:1. Enhancing real-world effectiveness of drug delivery to the patient:The device senses airflow and only releases the drug into the airstream when the inhalation parameters are suitable to optimise drug absorption thereby maximising the actual delivery of the drug during use.The device provides easy-to-understand real-time feedback to the patient on every use, indicating successful or unsuccessful drug administration. Thereby providing a continuous source of training in correct usage.2\. Providing information and analytical tools to the healthcare provider to better manage individual patients.The device intelligently collects patient data on how effectively they used the device and how frequently through the day. This can be used by clinicians and carers in personalising therapy, addressing non-adherence and understanding the outcomes of the medicine with individual patients. Addressing the quality, adherence and outcomes can then lead to reduced A&E attendance, better self-management and improved health for the patient. Furthermore, it creates a data set (which is not available today) which could introduce machine learning to adapt and personalise care for patients. Initially this will focus on the specific condition data but can be extended to the patient's comorbidity data and environmental data (eg air pollution level) which have an impact on exacerbations of the condition across patient groups.3\. Providing a large source of data to generate linkages between environmental factors (e.g. air quality data) and optimal preventative drug levels to manage chronic respiratory diseases."

电子呼吸器：用于给药的电子吸入装置，可提高给药效率和患者对呼吸系统疾病的依从性。一种吸入装置的开发旨在通过以下组合降低医疗成本并提高患者的治疗效果：增强给病人药物的实际有效性：该装置感应气流，只有当吸入参数适合优化药物吸收时才将药物释放到气流中，从而在使用过程中最大限度地提高药物的实际递送量。该设备在每次使用时向患者提供易于理解的实时反馈，表明药物给药成功或不成功。从而提供了正确使用的持续培训来源。向医疗保健提供者提供信息和分析工具，以更好地管理单个患者。该设备可以智能地收集患者使用该设备的效率以及一天中使用该设备的频率。这可以被临床医生和护理人员用于个性化治疗，解决不依从性和了解药物对个体患者的影响。解决质量、依从性和结果可以减少急诊室的出勤率，改善自我管理，改善患者的健康状况。此外，它创建了一个数据集（目前还没有），可以引入机器学习来适应和个性化患者护理。最初，这将侧重于具体的病情数据，但可以扩展到患者的合并症数据和环境数据（例如空气污染水平），这些数据对患者群体的病情恶化有影响。提供大量数据来源，以便在环境因素（例如空气质量数据）与管理慢性呼吸道疾病的最佳预防性药物水平之间建立联系。”