Enhanced identification of lung cancer nodules without CT by quantifying tissue elasticity

“几乎你认识的每个人都会在某个时候做过x光或扫描（无论是CT、MRI还是超声波）。通过这些不同的检查收集的数据对于创建内部身体图像非常有用，可以帮助医疗专业人员在诊断和治疗方面做出明智的决定。然而，一些功能数据很难通过影像学检查获得，例如，分析组织的拉伸或僵硬程度，这可以帮助识别和评估肿瘤和病变组织。相反，这可能需要一个侵入性的程序来获得可以分析的组织样本（活检）。Adaptix打算创造一种使用3D x射线数据的新方法，这些数据可以通过使用其创新的平板x射线源收集，来比较组织不同区域相对于周围组织的弹性。如果组织区域“变硬”，则可能表明疾病或肿瘤，并且与x光检查的其他信息一起，将有助于医生做出更早的诊断并使患者更快地开始相关治疗。Adaptix的愿景是为医疗专业人员提供一种便携式x射线设备，它涉及低剂量的辐射，可以用多种方式对关注的区域进行成像，不仅为他们提供该区域的详细3D x射线图像，而且还提供有关被观察组织弹性的重要信息。使Adaptix将这种医疗保健技术引入英国，将通过减轻系统负担和降低医疗保健成本来支持NHS，并为我们世界级的医疗保健专业人员提供更早、更准确的诊断。由于人口老龄化，自2009-10年以来，因疑似癌症而向医院紧急转诊的全科医生人数增加了90%，但转诊的10名患者中有9名未被诊断患有癌症。利用Adaptix的x射线源进行筛查，再加上组织硬度的详细信息，可以避免不必要的转诊和患者固有的压力。Adaptix是一家英国公司，希望在英国建立制造业，在英国创造就业机会。支持Adaptix将使其在英国的技术推向市场，这将使英国乃至全球的医疗保健受益。”

"Almost everyone you know will have had an X-ray or scan (whether CT, MRI or ultrasound) at some point. The data collected by these different examinations is very useful in enabling creation of an image of the internal body to help medical professionals make informed decisions about diagnoses and treatments.However, some functional data is hard to obtain using imaging examinations, for example, analysing how stretchy or stiff areas of tissue are, which can help in the identification and assessment of tumours and diseased tissue. Instead, this can require an invasive procedure to obtain a tissue sample that can be analysed (biopsy).Adaptix intends to create a new method of using 3D X-ray data, which can be collected by using its innovative Flat Panel X-ray Source, to compare how stretchy different areas of tissue are in relation to surrounding tissue. Where an area of tissue is 'stiffer' it may indicate disease or tumours, and along with the other information from the X-ray exam, will assist a medical practitioner in making an earlier diagnosis and starting patients on the relevant treatment sooner.Adaptix's vision is to provide medical professionals with a portable X-ray device, which involves low-doses of radiation, and can be used in multiple ways to image areas of concern, to provide them with not only detailed 3D X-ray images of the area but also vital information about the elasticity of the tissue being viewed.Enabling Adaptix to bring this healthcare technology to the UK, will support the NHS by removing burdens on the system and reducing the cost of healthcare, as well as equipping our world-class healthcare professionals to make earlier more accurate diagnoses.As a result of an ageing population, the number of urgent GP referrals to hospital for suspected cancer has increase by 90% since 2009-10, but 9 out of 10 patients who are referred are not diagnosed with cancer. Screening with Adaptix's X-ray source, enhanced by detailed information on tissue hardness, could prevent unnecessary referrals and the inherent stress for those patients.Adaptix is a UK company, looking to establish UK manufacturing, creating jobs in the UK. Supporting Adaptix will enable its UK technology to be brought to market, which will benefit the UK, as well as healthcare worldwide."