Enhanced identification of lung cancer nodules without CT by quantifying tissue elasticity

通过量化组织弹性，无需 CT 即可增强对肺癌结节的识别

• 批准号: 133590
• 金额: $ 6.37万
• 依托单位: ADAPTIX LIMITED
• 依托单位国家: 英国
• 项目类别: Feasibility Studies
• 财政年份: 2018
• 资助国家: 英国
• 起止时间: 2018 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=133590
• 关键词: Enhanced; identification; lung; cancer; nodules

"Almost everyone you know will have had an X-ray or scan (whether CT, MRI or ultrasound) at some point. The data collected by these different examinations is very useful in enabling creation of an image of the internal body to help medical professionals make informed decisions about diagnoses and treatments.However, some functional data is hard to obtain using imaging examinations, for example, analysing how stretchy or stiff areas of tissue are, which can help in the identification and assessment of tumours and diseased tissue. Instead, this can require an invasive procedure to obtain a tissue sample that can be analysed (biopsy).Adaptix intends to create a new method of using 3D X-ray data, which can be collected by using its innovative Flat Panel X-ray Source, to compare how stretchy different areas of tissue are in relation to surrounding tissue. Where an area of tissue is 'stiffer' it may indicate disease or tumours, and along with the other information from the X-ray exam, will assist a medical practitioner in making an earlier diagnosis and starting patients on the relevant treatment sooner.Adaptix's vision is to provide medical professionals with a portable X-ray device, which involves low-doses of radiation, and can be used in multiple ways to image areas of concern, to provide them with not only detailed 3D X-ray images of the area but also vital information about the elasticity of the tissue being viewed.Enabling Adaptix to bring this healthcare technology to the UK, will support the NHS by removing burdens on the system and reducing the cost of healthcare, as well as equipping our world-class healthcare professionals to make earlier more accurate diagnoses.As a result of an ageing population, the number of urgent GP referrals to hospital for suspected cancer has increase by 90% since 2009-10, but 9 out of 10 patients who are referred are not diagnosed with cancer. Screening with Adaptix's X-ray source, enhanced by detailed information on tissue hardness, could prevent unnecessary referrals and the inherent stress for those patients.Adaptix is a UK company, looking to establish UK manufacturing, creating jobs in the UK. Supporting Adaptix will enable its UK technology to be brought to market, which will benefit the UK, as well as healthcare worldwide."

“几乎你认识的每个人都会在某个时候做过X光或扫描（无论是CT、MRI还是超声波）。通过这些不同的检查收集的数据非常有用，可以创建内部身体的图像，帮助医疗专业人员做出明智的诊断和治疗决定。然而，一些功能数据很难通过成像检查获得，例如，分析组织的拉伸或僵硬区域，这有助于识别和评估肿瘤和病变组织。相反，这可能需要一个侵入性的程序来获得可以分析的组织样本（活检）。Adaptix打算创建一种新的方法，使用3D X射线数据，可以通过使用其创新的平板X射线源收集，以比较组织的不同区域与周围组织的拉伸程度。当组织区域“较硬”时，它可能指示疾病或肿瘤，并且沿着来自X射线检查的其他信息，将帮助医疗从业者做出早期诊断并更早地开始患者的相关治疗。Adaptix的愿景是为医疗专业人员提供便携式X射线设备，该设备涉及低剂量辐射，并且可以以多种方式用于对关注区域进行成像，不仅为他们提供该区域的详细3D X射线图像，还提供有关所观察组织弹性的重要信息。使Adaptix能够将这种医疗保健技术带到英国，将通过消除系统负担和降低医疗保健成本来支持NHS，并为我们世界一流的医疗保健专业人员提供装备，以便更早更准确地诊断。由于人口老龄化，自2009-10年以来，因疑似癌症而紧急转诊到医院的GP数量增加了90%，但10名转诊患者中有9名未被诊断出患有癌症。使用Adaptix的X射线源进行筛查，并通过组织硬度的详细信息进行增强，可以防止不必要的转诊和这些患者的内在压力。Adaptix是一家英国公司，希望在英国建立制造业，在英国创造就业机会。支持Adaptix将使其英国技术能够推向市场，这将使英国以及全球医疗保健受益。"