NMR STUDIES OF ISCHEMIC INJURY IN THE PERFUSED HEART

灌注心脏缺血性损伤的核磁共振研究

• 批准号: 2222377
• 负责人: MARTIN M PIKE
• 金额: $ 6.53万
• 依托单位: UNIVERSITY OF ALABAMA AT BIRMINGHAM
• 依托单位国家: 美国
• 财政年份: 1991
• 资助国家: 美国
• 起止时间: 1991-08-01 至 1997-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2222377
• 关键词: NMR; STUDIES; ISCHEMIC; INJURY; PERFUSED

项目成果

Nuclear magnetic resonance studies of cationic and energetic alterations with oxidant stress in the perfused heart. Modulation with pyruvate and lactate.

灌注心脏中氧化应激引起的阳离子和能量变化的核磁共振研究。

• DOI: 10.1161/01.res.77.4.773
• 发表时间: 1995
• 期刊: Circulation research
• 影响因子: 20.1
• 作者: Yanagida,S;Luo,CS;Doyle,M;Pohost,GM;Pike,MM
• 通讯作者: Pike,MM

The effect of K(atp)channel activation on myocardial cationic and energetic status during ischemia and reperfusion: role in cardioprotection.

K（atp）通道激活对缺血和再灌注期间心肌阳离子和能量状态的影响：在心脏保护中的作用。

• DOI: 10.1006/jmcc.2000.1328
• 发表时间: 2001
• 期刊: Journal of molecular and cellular cardiology.
• 作者: Fukuda,H;Luo,CS;Gu,X;Guo,L;Digerness,SB;Li,J;Pike,MM
• 通讯作者: Pike,MM

Early reperfusion levels of Na(+) and Ca(2+) are strongly associated with postischemic functional recovery but are disassociated from K(ATP) channel-induced cardioprotection.

Na()和Ca(2)的早期再灌注水平与缺血后功能恢复密切相关，但与K(ATP)通道诱导的心脏保护无关。

• DOI: 10.1016/j.yjmcc.2004.05.010
• 发表时间: 2004
• 期刊: Journal of molecular and cellular cardiology.
• 作者: Takayama,Eiichi;Guo,Ling-Ling;Digerness,StanleyB;Pike,MartinM
• 通讯作者: Pike,MartinM