Purification and bioactivity of legume protein as nutritional supplements

豆类蛋白的纯化及其作为营养补充剂的生物活性

• 批准号: LP190100130
• 负责人: Prof Philip Newsholme
• 金额: $ 21.99万
• 依托单位: Curtin University
• 依托单位国家: 澳大利亚
• 项目类别: Linkage Projects
• 财政年份: 2020
• 资助国家: 澳大利亚
• 起止时间: 2020-10-31 至 2023-11-30
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/LP190100130
• 关键词: Purification; bioactivity; legume; protein; nutritional

Lupin seed is a major Australian high protein legume crop, undervalued at only ~$200 tonne due to its use as an animal feed. However this project aims to add value to the crop by designing a scalable food-grade and commercialisable technology to purify the protein gamma-conglutin from lupin seed waste as a nutraceutical for human blood glucose control. The process optimisation and mechanism of action for gamma-conglutin will be informed by proteomic analysis and cellular studies. From the project farmers may benefit through adding a premium to their crop value, a new gamma-conglutin purification technology will be available for processors to commercialise and consumers will have a natural product to help their blood glucose control.

羽扇豆种子是澳大利亚主要的高蛋白豆类作物，由于用作动物饲料，其价值被低估，仅为约 200 美元吨。然而，该项目旨在通过设计一种可扩展的食品级和可商业化的技术来从羽扇豆种子废物中纯化蛋白质γ-羽扇豆凝集素作为人类血糖控制的营养保健品，从而为作物增加价值。蛋白质组分析和细胞研究将告知γ-球凝素的工艺优化和作用机制。从该项目中，农民可以通过增加农作物价值而受益，一种新的伽马凝集素纯化技术将可供加工商商业化，消费者将拥有一种天然产品来帮助他们控制血糖。