STRUCTURAL AND DYNAMIC STUDIES OF PROTEINS BY NMR
STRUCTURAL AND DYNAMIC STUDIES OF PROTEINS BY NMR
批准号:
2084027
负责人:
ROBERT A BECKMAN
金额:
$8.78万
依托单位国家:
美国
项目类别:
财政年份:
1989
资助国家:
美国
项目状态:
已结题
起止时间:
1989-07-01 至 1995-06-30
中文摘要
拟议的医师科学家培训计划将培训
英文摘要
The proposed Physician Scientist training program will train the
candidate in modern nuclear magnetic resonance (NMR) methods for
evaluation of structure and dynamics of macromolecules,
particularly proteins, and will deepen his appreciation of protein
structure-function relationships. The candidate will later apply
these techniques, together with his knowledge of enzyme kinetics,
to the study of medically significant molecules within his chosen
clinical area of pediatric hematology-oncology. The Phase I
training program includes three graduate courses (structure and
function of biological molecules, methods for their study, and
enzyme kinetics and mechanism), NMR tutorial with the sponsor,and
small projects which exploit ongoing research in the sponsor's
laboratory and which span the major current areas of NMR. One of
two projects will be undertaken during Phase II, with the choice
to be determined by feasibility as assessed at the beginning of
Phase II. Phase II project A involves a basic study of protein
folding, and Phase II project B involves NMR and kinetic studies
of a retroviral protease homologous to that from human
immunodeficiency virus I. The candidate's long range goal is to
use fundamental protein biophysics to contribute strategies for
rational drug design.
期刊论文(3)
专著(0)
科研奖励(0)
会议论文
Arteriotracheal fistula in patients treated for lymphoma.
接受淋巴瘤治疗的患者的动气管瘘。
DOI:
10.3109/15513818909037737
发表时间:
1989
期刊:
Pediatric pathology
影响因子:
--
作者:
[Dickman,PS, Nussbaum,E, Finkelstein,JZ]
通讯作者:
Finkelstein,JZ
DEVELOPMENTAL PROJECT--NMR HOMOLOGY MODELING
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批准号:6109103
-
项目类别:
-
资助金额:$0.0万
-
财政年份:1997
-
负责人:ROBERT A BECKMAN
-
依托单位:
STRUCTURAL & DYNAMIC STUDIES OF PROTEINS BY NMR
-
批准号:3085825
-
项目类别:
-
资助金额:$7.13万
-
财政年份:1989
-
负责人:ROBERT A BECKMAN
-
依托单位:
STRUCTURAL & DYNAMIC STUDIES OF PROTEINS BY NMR
-
批准号:3085823
-
项目类别:
-
资助金额:$5.86万
-
财政年份:1989
-
负责人:ROBERT A BECKMAN
-
依托单位:
STRUCTURAL & DYNAMIC STUDIES OF PROTEINS BY NMR
-
批准号:3085824
-
项目类别:
-
资助金额:$8.5万
-
财政年份:1989
-
负责人:ROBERT A BECKMAN
-
依托单位:
STRUCTURAL & DYNAMIC STUDIES OF PROTEINS BY NMR
-
批准号:3085822
-
项目类别:
-
资助金额:$5.67万
-
财政年份:1989
-
负责人:ROBERT A BECKMAN
-
依托单位:
海外基金