SES IMPACT ON RACIAL DIFFERENCES IN STROKE MORTALITY

SES 对中风死亡率种族差异的影响

• 批准号: 2231204
• 负责人: Lynne E Wagenknecht
• 金额: $ 6.18万
• 依托单位: WAKE FOREST UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1994
• 资助国家: 美国
• 起止时间: 1994-09-30 至 1996-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2231204
• 关键词: disease /disorder proneness /risk; geographic site; human data; human mortality; human population study; racial /ethnic difference; social support network; socioeconomics; stroke

Stroke mortality in the U.S. black population is generally recognized to be approximately 1.5 times that observed in the U.S. white population. There is a growing awareness that observed ethnic differences in mortality may be largely due to differences in socio-economic status (SES). Stroke mortality has been related to income, educational level, and other measures of SES. Because of the clear SES differences between U.S. racial groups, this may be acting as a confounder in the assessment of racial differences in stroke. In addition, the black excess stroke mortality is not consistent across all components of the population. For example, there is a four-fold black-to-white excess in stroke mortality at age 45, but by age 85 the black-to-white risk is approximately the same. Not only is identification of subgroups of blacks at extraordinary risk of great interest, but also it is reasonable to assume that the impact of SES may differ as a function of demographic, and other social support factors. This project will use data from the National Longitudinal Mortality Study (NLMS) to evaluate the proportion of the excess stroke mortality among the U.S. black population that is attributable to racial differences in SES. Secondary aims are to assess the impact of other demographic, geographic, and social support factors on racial differences in stroke mortality. These factors will be considered as a potential effect modifiers in the assessment of the role of SES on racial differences in stroke mortality. In addition, secondary analyses will be conducted to examine the impact of other factors in the data set (i.e., geographic variations in mortality rates) and the impact of SES on other diseases (i.e., ischemic heart disease).

美国黑人人口的中风死亡率通常被认为是 大约是美国白人人口的1.5倍。 越来越多的人意识到了死亡率的种族差异 这在很大程度上可能是由于社会经济地位的差异。卒中 死亡率与收入、教育水平和其他因素有关 SES的衡量标准。因为美国种族之间存在明显的SES差异 群体，这可能会在种族评估中起到混淆的作用 中风的差异。此外，黑人超额中风死亡率是 在人口的所有组成部分中并不是一致的。例如, 在45岁时，中风死亡率是黑人和白人的四倍， 但到85岁时，从黑到白的风险大致相同。不仅 识别黑人亚群是否有极大的风险 利息，但也有理由认为，SES的影响可能 作为人口统计和其他社会支持因素的函数而不同。 该项目将使用来自国家纵向死亡率研究的数据 (NLMS)评估卒中超额死亡率在 可归因于SES中的种族差异的美国黑人人口。 次要目标是评估其他人口、地理、 以及社会支持因素对中风死亡率种族差异的影响。 这些因素将被视为潜在的效果修饰物 评估SES在中风死亡率中的种族差异中的作用。 此外，还将进行二次分析，以检查 数据集中的其他因素(即死亡率的地理差异 发病率)以及SES对其他疾病(如缺血性心脏病)的影响 疾病)。