PROTEIN PHOSPHATASES--1994 FASEB CONFERENCE

蛋白质磷酸酶--1994 FASEB 会议

• 批准号: 2107525
• 负责人: DAVID L. BRAUTIGAN
• 金额: $ 0.4万
• 依托单位: FEDERATION OF AMER SOC FOR EXPER BIOLOGY
• 依托单位国家: 美国
• 财政年份: 1994
• 资助国家: 美国
• 起止时间: 1994-07-18 至 1995-07-17
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2107525
• 关键词: meeting /conference /symposium; phosphoprotein phosphatase

In July 1994 the Federation of American Societies for Experimental Biology (FASEB) will convene an international conference on Protein Phosphatases at Copper Mountain, Colorado. This will be the third such conference, and it has been authorized by FASEB because of the success of the 1990 and 1992 conferences. This application seeks partial support for the operation of this conference. Research on protein phosphatases is proceeding at a brisk pace, revealing the fundamental importance and unexpected complexity of these enzymes in the signal transduction pathways that govern cell growth and physiology. Within the past year dozens of new phosphatases and phosphatase regulatory subunits have been cloned. Now there is appreciation that protein phosphatases initiate important intracellular events such as T cell activation and G2 to M progression. Protein phosphatases offer vast potential for development of new and specific pharmacologic agents. Particular phosphatases already have been identified as the targets for the immunosuppressant drugs cyclosporin A and the target for tumor promoter compounds such as okadaic acid and calyculin A. Proteins encoded by DNA tumor viruses also target phosphatases inside cells and form stable complexes to transform cells. Like other FASEB summer conferences this meeting will select about 150 participants from applications, including representatives from industry and academia, including senior scientists, postdocs, and graduate students. There is a constant infusion of new researchers into this area and the 1994 conference will be important for a focused, yet comprehensive, introduction to the genetics, biochemistry, and cell biology of protein phosphatases. The Conference will consist of eight sessions, each with a discussion leader and four speakers who will be selected from investigators that have made important recent contributions. In addition two poster sessions will be organized, with published abstracts. At the last Conference more than eighty posters were presented for two days each providing an important format for scientific exchanges. Inclusion of women, minorities, and students as speakers and participants is a special priority. The 1994 summer conference on Protein Phosphatases will orient researchers, disseminate information and identify areas for new investigations.

1994年7月，美国实验生物学学会联合会（Federation of American Societies for Experimental Biology） （FASEB）将召开蛋白磷酸酶国际会议 在科罗拉多的铜山 这将是第三次这样的会议， 由于1990年的成功， 1992年会议。 本申请寻求部分支持， 这次会议的运作。 蛋白磷酸酶的研究正在以轻快的步伐进行，揭示了 这些酶的根本重要性和意想不到的复杂性， 控制细胞生长和生理的信号转导途径。 在过去的一年中，数十种新的磷酸酶和磷酸酶调节 亚单位已被克隆。 现在人们认识到蛋白质 磷酸酶启动重要的细胞内事件，如T细胞 活化和G2至M进展。 蛋白磷酸酶提供了巨大的 开发新的和特定的药理学试剂的潜力。 特定的磷酸酶已经被鉴定为 免疫抑制剂环孢素A与肿瘤靶点 促进剂化合物如冈田酸和calyculin A。 编码的蛋白质 通过DNA，肿瘤病毒也靶向细胞内的磷酸酶， 复合物转化细胞。 像其他FASEB夏季会议，本次会议将选择约150 应用程序的参与者，包括工业界代表 和学术界，包括高级科学家，博士后和研究生 学生 不断有新的研究人员进入这一领域 1994年的会议将是一个重点突出但 全面介绍遗传学、生物化学和细胞 蛋白磷酸酶生物学 会议将由八个 会议，每个会议有一个讨论领导人和四个发言人，他们将 从最近做出重要贡献的研究人员中选出。 此外，还将组织两次海报会议， 摘要。 在上次会议上， 为期两天，为科学交流提供了重要形式。 让妇女、少数民族和学生作为发言者和参与者 是一个特殊的优先事项。 1994年蛋白磷酸酶夏季会议 将指导研究人员，传播信息，并确定 新的调查