FASEB CONFERENCE--VIRUS ASSEMBLY

请求为题为“病毒大会”的会议提供部分支助，以 由美国协会联合会主办 实验生物学(FASE B)，1994年7月23日至7月28日，在佛蒙特州 佛蒙特州萨克斯顿河学院。向美国国立卫生研究院寻求资金 特别是为了向年轻调查人员提供支持 来参加这次会议。这次会议的目的是使 科学家共同研究病毒组装和结构的方方面面 (包括与病毒进入相关的初始拆卸步骤 细胞)用于细菌、植物、动物和人类病毒。其意图是 鼓励交流有关病毒组装的想法和假设 和结构，跨越常见的分类障碍，并促进 传播通过各种不同病毒获得的结果 使用各种不同的实验方法，包括强大的 生化和遗传学方法以及X射线结晶学、电子 显微技术和图像重建。该计划将强调使用 的结构信息来设计预防和治疗性抗肿瘤 病毒制剂(包括抗艾滋病毒药物)，除了基本的 生物现象和进化关系。没有其他人 完全致力于病毒组装和结构问题的会议， 除了前两次在1990年举行的关于这一主题的FASEB会议和 1992年。本系列的前几次会议都非常成功 并达到了预期的沟通效果。这看起来很有可能，考虑到 目前这一领域的进展速度，即FASEB会议 1994年将是正在进行的关于以下主题的一系列会议的第三次会议 病毒的组装和结构。

Partial support is requested for a conference entitled "Virus Assembly" to be held under the auspices of the Federation of American Societies of Experimental Biology (FASEB) from July 23 to July 28, 1994, at the Vermont Academy, Saxtons River, Vermont. Funds are sought from the NIH specifically for the purpose of providing support for young investigators to attend this conference. The purpose of the conference is to bring together scientists working on all aspects of virus assembly and structure (including the initial disassembly steps associated with viral entry into cells) for bacterial, plant, animal and human viruses. The intention is to encourage communication of ideas and hypotheses about virus assembly and structure, across the usual taxonomic barriers, and to promote dissemination of results obtained with a variety of different viruses using a variety of different experimental approaches, including powerful biochemical and genetic methods as well as X-ray crystallography, electron microscopy and image reconstruction. The program will emphasize the use of structural information to design prophylactic and therapeutic anti- viral agents (including anti-HIV agents), in addition to the basic biological phenomena and evolutionary relationships. There are no other conferences devoted entirely to problems of virus assembly and structure, except the previous two FASEB conferences on this topic held in 1990 and 1992. The previous conferences in this series were enormously successful and achieved the kind of communication desired. It seems likely, given the current rate of progress in this field, that the FASEB conference of 1994 will be the third in an ongoing series of conferences on the topic of virus assembly and structure.