SIXTH INTERNATIONAL CONFERENCE ON CHRONOPHARMACOLOGY

第六届国际时间药理学会议

• 批准号: 2105063
• 负责人: ERHARD HAUS
• 金额: $ 1.3万
• 依托单位: RAMSEY FOUNDATION
• 依托单位国家: 美国
• 财政年份: 1994
• 资助国家: 美国
• 起止时间: 1994-05-16 至 1995-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2105063
• 关键词: bioperiodicity; meeting /conference /symposium; pharmacokinetics; pharmacology; travel

The Sixth International Conference on Chronopharmacology will be held in Amelia Island, Florida, from July 6 to July 9, 1994. The Conference will summarize the current knowledge on time dependent rhythmic changes in pharmacokinetics and pharmacodynamics which occur as a function of biologic rhythms of different frequencies and will discuss their implications for drug development, drug testing, and medical practice. The Conference will consist of five symposia with presentations by invited speakers. The topics will be: "The Design of Chronopharmacologic Studies", "Chronopharmacology in Drug Development", "Chronopharmacology in Neuropsychiatry", "Rhythms as Biomarkers", and "Biologic Rhythm in Clinical Practice". each symposium will be supplemented by a workshop on the same topic. New peer reviewed material will be presented in sessions on "Cardiovascular Chronopharmacology" (3), the "Chronopharmacology of Cancer" (2), "Gastrointestinal Chronopharmacology", "Pulmonary Chronopharmacology," Chronopharmacology of Pain" (1 each) and four sessions on general chronopharmacology. These sessions will also be supplemented by luncheon or evening workshops. It is the aim of this Conference to bring the new developments in the field of chronopharmacology and chronotherapeutics and the methodology necessary for their application to the attention of healthcare workers at all levels and of pharmaceutical scientists involved in drug development and drug testing, and in turn receive their input for further development of chronotherapeutic treatment regimen. The introduction of chronopharmacologic methods is expected to optimize drug development and drug testing by introducing techniques which take into account the biologic variations in pharmacokinetics and pharmacodynamics in the experimental animals and/or human subjects to be treated. In drug development and drug testing, the choosing of the "right" time will greatly improve the accuracy and precision of the results obtained and avoid misleading results and potential damage to patients. In its application to patients, this approach aims at treating patients at a time (circadian or other) when the desired effects are maximal and the undesirable side-effects minimized. Increased precision in drug testing and improved treatment results with medications given at the time when needed and optimally effective will lead to a decrease in cost of drug testing and of medical care.

第六届国际时间药理学会议将于#年举行 佛罗里达州阿米莉亚岛，1994年7月6日至7月9日。大会将 总结了目前关于时间相关节律变化的知识 药代动力学和药效学作为以下因素的函数 不同频率的生物节律，并将讨论其 对药物开发、药物测试和医疗实践的影响。 会议将由五个专题讨论会组成，应邀发表演讲 扬声器。主题是：“时间药物学的设计” 研究“，”药物开发中的时间药理学“，”药物开发中的时间药理学“ 《神经精神病学》、《作为生物标记物的节律》和《生物节律》 临床实践“。每一次研讨会都将辅以一个关于 同样的话题。新的同行评议材料将在会议中提交 关于“心血管时间药理学”(3)、“心血管时间药理学” “癌症”(2)、“胃肠时间药理学”、“肺” 时间药理学，“疼痛的时间药理学”(各1名)和4名 关于普通时间药理学的会议。这些会议也将是 辅以午餐或晚间工作坊。这就是我们的目的 会议将带来该领域的新发展 时间药理学和时间治疗学以及必要的方法学 以引起各级医护人员的注意 以及参与药物开发和药物开发的制药科学家 测试，并反过来接收他们的投入，以便进一步开发 计时治疗方案。介绍了 时间药理学方法有望优化药物开发和 通过引入技术来进行药物测试，这些技术考虑了 大鼠体内药代动力学和药效学的生物变异 待治疗的实验动物和/或人类受试者。在毒品方面 开发和药物测试，选择正确的时间将 大大提高了所获得结果的准确度和精密度 避免误导结果和对患者的潜在损害。在ITS中 应用于患者，这种方法旨在一次治疗患者 (昼夜节律的或其他的)当期望的效果最大并且 不良副作用降至最低。提高药物检测的准确性 并改善了在以下情况下给予的药物的治疗结果 所需的最佳效果将导致药品成本的降低 测试和医疗护理。