Evolving the bionic bladder: supporting a sustainable transition to a next generation neurotechnology to restore bladder control following spinal cord injury

进化仿生膀胱：支持向下一代神经技术的可持续过渡，以恢复脊髓损伤后的膀胱控制

• 批准号: 53298
• 金额: $ 13.54万
• 依托单位: UNIVERSITY COLLEGE LONDON
• 依托单位国家: 英国
• 项目类别: Study
• 财政年份: 2020
• 资助国家: 英国
• 起止时间: 2020 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=53298
• 关键词: Evolving; bionic; bladder; supporting; sustainable

Injury or disease affecting the spinal cord or brain significantly affects how the bladder functions. It can destroy the ability to empty the bladder, cause unwanted contractions that lead to incontinence, and alter or remove the sensation that the bladder needs emptying. These dysfunctions require the use of catheters, can lead to frequent urinary tract infections and in the long-term may cause damage to the kidneys, extending the effects beyond the day-to-day impact of regular incontinence.Finetech Medical has manufactured an implant that restores control over the bladder for people with spinal cord injuries for over 30 years. The implant requires updating to meet the changing needs of patient (due to improved care after injury), and new regulatory requirements.This project will involve a scientist from University College London working in Finetech Medical to assist in redesigning the therapy, to reflect the latest science and technology, and to be sustainable for the future. We expect that this will provide an improved therapy for people living with bladder disorders, that will be available to a greater number of patients.

影响脊髓或大脑的损伤或疾病会显著影响膀胱的功能。它可以破坏排空膀胱的能力，引起不必要的收缩，导致失禁，并改变或消除膀胱需要排空的感觉。这些功能障碍需要使用导尿管，可能导致频繁的尿路感染，长期可能会对肾脏造成损害，其影响超出日常的日常影响。Finetech Medical制造了一种植入物，可以恢复对脊髓损伤患者的膀胱控制超过30年。植入物需要更新以满足患者不断变化的需求（由于损伤后护理的改善）和新的监管要求。该项目将涉及一名来自伦敦大学学院在Finetech Medical工作的科学家，以协助重新设计疗法，以反映最新的科学技术，并可持续发展。我们预计，这将为膀胱疾病患者提供更好的治疗方法，并将提供给更多的患者。