Programmed cell death signalling in innate immunity

该提案旨在解决程序性细胞死亡促进先天免疫细胞信号传导的潜力，这是一个关键且基本的生物过程。它旨在利用创新的跨学科方法产生细胞死亡和先天信号传导领域的新知识，并发现影响先天炎症反应的新分子。该项目的预期成果是增强我们对细胞死亡的基本了解，并建立跨学科合作。这项工作将为澳大利亚人的经济和健康带来重大利益，因为它有望识别出制药和生物技术行业感兴趣的分子。

This proposal aims to address the under-explored potential for programmed cell death to promote innate immune cell signalling, which is a critical and fundamental biological process. It aims to generate new knowledge in the areas of cell death and innate signalling using innovative interdisciplinary approaches and discover new molecules that impact innate inflammatory responses. The expected outcomes of this project are to enhance our basic understanding of cell death, and build interdisciplinary collaborations. This work should provide significant benefit to the economy and health of Australians, as it is expected to identify molecules that will be of interest to the pharmaceutical and biotechnology industries.