BREAST CANCER IN ORIENTAL AMERICANS

乳腺癌被认为与一个富裕的，高脂肪的 饮食，但很少有这种癌症的病例对照研究已经能够 以证明假定存在的强烈饮食关联。 由于日本本土和中国女性患有乳腺癌 死亡率大约是美国白色人的五分之一 女性，乳腺癌发病率连续几代上升， 移民到美国的亚裔家庭， 研究人群可能提供充分异质性风险 乳腺癌的早期诊断， 协会. 因此，NCI EEB决定启动病例对照研究， 中国、日本和美国女性乳腺癌研究 旧金山-奥克兰SMSA中的菲律宾遗产（标准 大都会统计区）、洛杉矶SMSA和俄勒冈州， 夏威夷--美国仅有的三个人口众多的地区 亚裔美国居民和基于人群的癌症登记处。 据推测，儿童和青少年时期的饮食 可能比成人饮食更重要， 乳腺癌 为了评估早期和成人的作用， 饮食，所选的受试者是55岁或更少，因此， 他们和他们的母亲可以就这些问题接受采访， 早期饮食

Breast cancer is believed to be related to an affluent, high-fat diet, yet few case-control studies of this cancer have been able to demonstrate the strong dietary associations presumed to exist. Since native Japanese and Chinese women have breast cancer mortality rates approximately one-fifth those of white American women, and breast cancer rates rise in successive generations among Asian families who migrate to the United States, an Asian American study population might provide a sufficiently heterogeneous risk of breast cancer to permit detection of the underlying associations. Thus, the NCI EEB decided to initiate a case-control study of breast cancer among women of Chinese, Japanese, and Filipino heritage in the San Francisco-Oakland SMSA (Standard Metropolitan Statistical Area), the Los Angeles SMSA, and Oahu, Hawaii-the only three areas of the United States with large number of Asian-American residents and population-based cancer registries. It has been hypothesized that diet during childhood and adolescence may be more crucial than adult diet in determining the risk of breast cancer. To assess the role of early, as well as adult, diet, the subjects selected were 55 years or less, so that both they and, their mothers could be interviewed about the subjects, early diet.