BREAST CANCER IN ORIENTAL AMERICANS

乳腺癌被认为与富裕的、高脂肪的 饮食，然而关于这种癌症的病例对照研究很少 以证明推定存在的强烈的饮食联系。 由于土生土长的日本和中国妇女患有乳腺癌 死亡率约为美国白人的五分之一 女性，乳腺癌发病率在几代人中不断上升 移民到美国的亚裔家庭，亚裔美国人 研究人群可能会提供一个足够不同的风险 以允许检测到潜在的 联想。因此，NCI EEB决定启动病例对照研究 中国、日本和日本女性乳腺癌的研究 旧金山的菲律宾传统-奥克兰SMSA(标准 大都会统计局)、洛杉矶SMSA和瓦胡岛， 夏威夷--美国仅有的三个人口众多的地区 亚裔美国居民和以人口为基础的癌症登记。 据推测，儿童和青春期的饮食 可能比成人饮食更重要，在确定风险 乳腺癌。评估早期和成人的作用， 饮食，选定的受试者年龄在55岁或以下，所以两者 他们和他们的母亲可以就这些话题接受采访， 早期节食。

Breast cancer is believed to be related to an affluent, high-fat diet, yet few case-control studies of this cancer have been able to demonstrate the strong dietary associations presumed to exist. Since native Japanese and Chinese women have breast cancer mortality rates approximately one-fifth those of white American women, and breast cancer rates rise in successive generations among Asian families who migrate to the United States, an Asian American study population might provide a sufficiently heterogeneous risk of breast cancer to permit detection of the underlying associations. Thus, the NCI EEB decided to initiate a case-control study of breast cancer among women of Chinese, Japanese, and Filipino heritage in the San Francisco-Oakland SMSA (Standard Metropolitan Statistical Area), the Los Angeles SMSA, and Oahu, Hawaii-the only three areas of the United States with large number of Asian-American residents and population-based cancer registries. It has been hypothesized that diet during childhood and adolescence may be more crucial than adult diet in determining the risk of breast cancer. To assess the role of early, as well as adult, diet, the subjects selected were 55 years or less, so that both they and, their mothers could be interviewed about the subjects, early diet.