EVALUATION OF COMPOUNDS FOR ABUSE POTENTIAL IN BABOONS

这份合同的目的是获取有关滥用职权的信息 不同药物静脉和口服给药途径的潜力 实验室灵长类动物的管理。具体地说，承包商将 被要求专注于生成与相对滥用有关的数据 自身给药药物的潜在应用前景 复杂而灵敏的实验室方法来评估相对滥用 药物类别内和药物类别之间化合物的责任。这些数据 需要满足，至少部分地，国家药物研究所 滥用提供关于滥用的信息的法定义务 卫生与公众服务部(HHS)的药物潜力。 生成的数据将用于食品和药物管理局(FDA) 和药品监督管理局(DEA)提出建议 和决定，分别与药品在《 1970年《管制物质法》(PL 91-513)和国际毒品 管制条约(单一公约和精神药物公约)。

The objective of this contract is to obtain information regarding abuse potential of various drugs by intravenous and oral routes of administration in laboratory primates. Specifically the contractor will be asked to focus on generating data pertaining to relative abuse potential of self-administered pharmacological agents by means of sophisticated and sensitive laboratory methods to assess relative abuse liability of compounds both within and between drug classes. These data are needed to fulfill, at least in part, the National Institute on Drug Abuse statutory obligation to generate information concerning abuse potential of drugs for the Department of Health and Human Services (HHS). The data generated will be used by the Food and Drug Administration (FDA) and the Drug Enforcement Administration (DEA) for making recommendations and decisions, respectively, pertaining to scheduling of drugs under the Controlled Substances Act of 1970 (PL 91-513) and international drug control treaties (Single Convention and the Psychotropic Convention).