META-ANALYSIS OF DRUG ABUSE TREATMENT OUTCOME STUDIES

药物滥用治疗结果研究的荟萃分析

• 批准号: 3635541
• 负责人: DAVID M FRAM
• 金额: $ 9.63万
• 依托单位: BELMONT RESEARCH, INC.
• 依托单位国家: 美国
• 财政年份: 1995
• 资助国家: 美国
• 起止时间: 1995-04-01 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/3635541
• 关键词: computer data analysis; computer program /software; drug abuse information system; drug abuse therapy; human therapy evaluation; prognosis; statistics /biometry

The goal of this project is to provide the database infrastructure and software tools necessary to enable quantitative integration of published drug abuse treatment outcome studies. These facilities will allow health services researchers to take advantage of meta-analytic techniques to gain clearer insight into drug abuse treatment effectiveness than what can be achieved through the traditional narrative research overview. The Phase I project will consist of several activities designed to establish a baseline meta-analysis framework, including: (1) collection and abstraction of the relevant literature; (2) design and construction of a database to store the abstracted study parameters; (3) selection and integration of appropriate statistical software; and (4) development of mechanisms for regular updating and dissemination of the database and associated software. Building on this framework, Phase II of the project will focus on carrying out a variety of meta-analyses in order to generate estimates of treatment effectiveness that take into account such covariates as drug type, treatment modality, and client demographics. The Phase III commercialization activities might include on-going maintenance and enhancement of the drug abuse treatment outcome research database as well as adaptation of the approach to other important public health domains.

该项目的目标是提供数据库基础设施和 实现已发表的定量整合所必需的软件工具 药物滥用治疗结果研究。这些设施将使健康 服务研究人员利用元分析技术来获得 比以往任何时候都更清楚地了解药物滥用治疗的效果 通过对传统叙事研究的概述来实现。 第一阶段项目将包括多项活动，旨在 建立基线荟萃分析框架，包括：（1）收集和 相关文献的摘要； (2) 设计与施工 数据库存储提取的研究参数； (3)选型与 整合适当的统计软件； (4) 发展 定期更新和传播数据库的机制 相关软件。 在此框架的基础上，项目二期将重点开展 进行各种荟萃分析以生成治疗估计 考虑药物类型等协变量的有效性， 治疗方式和客户人口统计数据。第三期 商业化活动可能包括持续的维护和 还加强药物滥用治疗结果研究数据库 作为该方法对其他重要公共卫生领域的调整。