CONFERENCE ON BONE/CARTILAGE/COLLAGEN--GROWTH & DEVELOP

会议将重点讨论对增长和分化的控制 这具骨架的。重点将放在骨骼的基因控制上 发育和图案化、骨和软骨谱系以及骨生长 在成人身上。重点将放在了解导致 骨骼与未修饰间充质的区别。会有的 还分析了对现有骨骼重塑的控制和 影响成骨细胞和破骨细胞功能的因素。这些 这些发现与人类疾病有关，就像大脑中的 儿童骨骼的生长、发育和重塑。 生物学原理对仍然知之甚少的 人类的主要疾病，如骨质疏松症，将被审查。科学 会议将结合从正常哺乳动物发育中学到的经验教训 骨骼和骨骼元素--尤其是细胞机械--到 无脊椎动物物种。最后，将强调临床相关性。 在适用的情况下。

The Conference will focus on control of the growth and differentiation of the skeleton. Emphasis will be on genetic control of skeletal development and patterning, bone and cartilage lineage, and bone growth in the adult. The focus will be on understanding events leading to the differentiation of the skeleton from unmodified mesenchyme. There will also be an analysis of the control of remodelling of existing bone and factors that influence the function of osteoblasts and osteoclasts. These findings are pertinent to human disease, as with abnormalities in the growth, development, and remodelling of the skeleton in children. Implications of the biological principles for still-poorly understood major human diseases, such as osteoporosis, will be reviewed. Scientific sessions will combine lessons learned from normal mammalian development of the skeleton and skeletal elements--especially cellular machinery--to invertebrate species. Finally, clinical correlations will be stressed wherever applicable.