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Advanced Therapy Medicinal Products Using Silicon Nano Drug BioCourier Optimized Using Deep Learning A.I,

Advanced Therapy Medicinal Products Using Silicon Nano Drug BioCourier Optimized Using Deep Learning A.I,
使用深度学习人工智能优化的硅纳米药物 BioCourier 的先进治疗药物产品,
批准号:
65047
负责人:
金额:
$5.99万
依托单位:
依托单位国家:
英国
项目类别:
Responsive Strategy and Planning
财政年份:
2021
资助国家:
英国
项目状态:
已结题
起止时间:
2021 至 --

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中文摘要
翻译
* *背景。**在2019冠状病毒病大流行期间,我们迫切需要能够在紧急情况下迅速部署的疾病控制工具,并且更加需要能够迅速将现有药物重新用于一种疾病综合征的新适应症,这种疾病综合征会导致从轻微到非常严重的一系列疾病后果。**药物传递载体技术**可以大大提高药物的性能,减少药物的副作用,并允许使用侵入性较小的药物传递途径(例如片剂而不是注射)。由于我们正处于COVID-19大流行期间,因此产生了大量关于该疾病及其后果的数据,以及不同药物和医疗干预措施的试验。这使得对结果的解释具有挑战性,并且不容易确定新的疾病治疗方法。然而,人工智能系统可以使用算法来处理数百万个数据点来解决非常具体的问题。因此,在本项目中,研究将采用深度学习人工智能**结合非常专业的**药物输送技术**来快速评估大量数据,以确定疾病、药物输送和正在试验的药物类型之间的新关系,从而确定重点关注的新产品,以便全面临床开发用于未来COVID和相关疾病治疗的干预治疗。**这将与优化药物输送和药物靶向有关,以获得更有效和安全的治疗方法
英文摘要
**Background.**It has emerged through the COVID-19 pandemic outbreak that there is a significant need to have disease control tools that can be rapidly deployed in an emergency situation and an increased need to be able to rapidly repurpose existing drugs for new indications for a disease syndrome that induces a range of disease outcomes from mild to very severe.**Drug delivery carrier technologies** can greatly enhance the performance of drugs, reduce the side effects of drugs, and allow less invasive drug delivery routes to be used (for example a tablet instead of an injection).As we are in the middle of a COVID-19 pandemic there is a vast amount of data being generated on the disease and the disease outcomes, trialling of different drugs and medical interventions. This makes interpretation of outcomes challenging and does not readily allow identificaiton of new disaese therapies. However artificial intelligence system can use algorithms to go through millions of data points to solve very specific problems.Therefore in this project, studies will employ **deep learning artificial intelligence** in combination with a very specialised **drug delivery technology** to rapidly assess vast amounts of data to identify new relations ships between disease, drug delivery and they types of drugs being trialled in order to determine new products to focus on for full clinical development for intervention therapy for future COVID and related disease treatments.**Main Areas of Focus**This will be related to optimising drug delivery and drug targeting for more effective and safe therapies
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