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EFFECT OF PAROXETINE ON THIOTHIXENE PHARMACOKINETICS

EFFECT OF PAROXETINE ON THIOTHIXENE PHARMACOKINETICS
帕罗西汀对噻吩药代动力学的影响
批准号:
5216214
负责人:
SALLY K GUTHRIE
金额:
$0.0万
依托单位:
--
依托单位国家:
美国
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财政年份:
--
资助国家:
美国
项目状态:
未结题
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英文摘要
The aim of this research is to determine how the pharmacokinetic parameters of cis-thiothixene are affected by concomitant administration of paroxetine. Paroxetine is a potent inhibitor of CYP2D6, which may be an important pathway for the elimination of thiothixene. Thiothixene plasma concentrations will be determined using high-performance liquid chromatography.
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