CRC FOR THE STUDY OF SCHIZOPHRENIA & PSYCHIATRIC REHAB.

CRC 用于精神分裂症研究

• 批准号: 2373044
• 负责人: ROBERT P LIBERMAN
• 金额: $ 146.59万
• 依托单位: UNIVERSITY OF CALIFORNIA LOS ANGELES
• 依托单位国家: 美国
• 财政年份: 1977
• 资助国家: 美国
• 起止时间: 1977-09-29 至 2000-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2373044
• 关键词: biomedical facility; clinical research; schizophrenia

The CRC for Schizophrenia is a multidisciplinary organization of scientists conducting research and development of diagnostic, assessment and treatment methods and providing core research services to independently funded projects comprising psychobiological studies of etiology, course and outcome and biobehavioral treatment effects on schizophrenia and other serious mental disorders. A heuristic vulnerability-stress-protective factors conceptual framework of schizophrenia guides hypothesis-driven research and, in return, is informed by project findings. Longitudinal studies are multidimensional in determining the interplay of genetic, developmental, neurocognitive, socio-behavioral, family, and psychophysiological factors on psychopathology and psychosocial functioning. The CRC consists of core labs that provide direct and consultative research services to integral and affiliated projects in areas of diagnosis/psychopathology, family processes, cognition/psychophysiology/neuropsychology, behavioral assessment and social skills, psychopharmacology, and methodology and statistics. Core labs also conduct research and development on instrumentation and pilot studies in promising areas, resulting in applications for independent, extramural support for new projects. Priority in the CRC is given to the development and validation of innovative and integrated drug and psychosocial treatment and rehabilitation interventions that are designed from knowledge gained through studies that identify predictors and correlates of course and outcome of schizophrenic disorders. Research is conducted with quality assurance procedures that maintain rigorous, reliable, and ethical pursuit of data through Center-wide, criterion-based training of assessors, audits, peer consultation, and monitoring. Research training is carried out with pre-and postdoctoral and visiting clinical research fellows through apprenticeships with CRC faculty. In the past five years, more than 50 fellows received training at the CRC, many of them continuing to collaborate with the CRC after launching their research careers elsewhere. Cross-validation, replication and dissemination of research methods and novel treatments is accomplished through collaborative studies with other investigators throughout the USA and the world. Adaptation and utilization of CRC findings are promoted among mental health clinicians through workshops, publications, manuals, and video-assisted treatment modules to bridge the gap between research and practice.

精神分裂症儿童研究中心是一个多学科的组织， 科学家进行诊断、评估的研究和开发 和治疗方法，并提供核心研究服务 独立资助的项目，包括心理生物学研究 脑瘫的病因、病程、转归及生物行为治疗效果 精神分裂症和其他严重的精神障碍。启发式方法 脆弱-压力-保护因素概念框架 精神分裂症指导着以假设为导向的研究，反过来， 由项目调查结果提供信息。纵向研究是多维的。 在决定遗传、发育、神经认知、 社会行为、家庭和心理生理因素对 精神病理学和心理社会功能。 CRC由核心实验室组成，这些实验室提供直接和咨询 为以下领域的综合项目和附属项目提供研究服务 诊断/精神病理学，家庭过程， 认知/心理生理学/神经心理学、行为评估和 社交技能、精神药理学、方法论和统计学。堆芯 实验室还进行仪器设备和试点的研究和开发 在前景看好的领域进行研究，导致申请独立、 为新项目提供外部支持。 在《儿童权利公约》中，优先考虑开发和验证 创新和综合的药物和心理社会治疗和 根据所获得的知识设计的康复干预措施 通过研究确定预测因素和相关因素，当然， 精神分裂症的结局。研究是有质量的 保证程序保持严格、可靠和合乎道德 通过中心范围内基于标准的培训来追求数据 评估员、审计、同行咨询和监督。 研究性培训包括博士后和博士后访问 通过与CRC教员的学徒关系进行临床研究。在……里面 在过去的五年中，50多名研究员在CRC接受了培训， 他们中的许多人在推出他们的 在其他地方从事研究工作。交叉验证、复制和 研究方法和新疗法的传播已经完成 通过与美国各地的其他研究人员合作进行研究 还有这个世界。促进对儿童权利公约成果的改编和利用 通过研讨会、出版物、手册、 和视频辅助治疗模块，以缩小研究之间的差距 和练习。