AUDITORY/MOTOR NEURAL ACTIVITY DURING BIRD SONG LEARNING

鸟鸣学习过程中的听觉/运动神经活动

• 批准号: 2519699
• 负责人: Amish S Dave
• 金额: $ 2.02万
• 依托单位: UNIVERSITY OF CHICAGO
• 依托单位国家: 美国
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-03-19 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/2519699
• 关键词: Aves; animal communication behavior; auditory stimulus; behavioral /social science research tag; brain electrical activity; caudate nucleus; electronic recording system; implant; neural information processing; sensorimotor system; vocalization

Birdsong is an excellent model system for investigating the neural correlates of sensorimotor integration and learning of complex behavior. Much attention has focused on the study of auditory processes in the vocal motor pathways; these efforts have largely occurred in adult, anesthetized birds after learning has already occurred. A recent breakthrough in the sponsor's lab allows chronic single-unit recordings in singing birds; the proposed research will apply these techniques to study sensory and motor activity in song system nuclei in two sets of experiments. 1) motor activity will be characterized in HVc and RA (nuclei involved in moment to moment control of song), and in Area X and 1MAN (nuclei necessary for song learning) in juvenile zebra finches (Taeniopygia guttata) during song learning. Development of the temporal hierarchical organization of the adult motor pathway will be studied. 2) Auditory activity will be characterized in the same nuclei, allowing the distribution of song system auditory neurons and development of auditory selectivity for the bird's own song to be studied. Use of chronic techniques will address the recent finding that anesthetics significantly alter the distribution of song system auditory activity.

BirdSong是研究神经的一个很好的模型系统 感觉-运动整合与复合体学习的相关研究 行为。听觉的研究一直是人们关注的焦点。 发声运动通路中的过程；这些努力在很大程度上 发生在成鸟身上，麻醉后的鸟类经过学习已经 发生了。赞助商实验室最近的一项突破使慢性 歌唱鸟儿的单单元录音；拟议的研究将适用 这些技术用于研究歌唱系统中的感觉和运动活动 两组实验中的原子核。1)运动活动将是 以HVC和RA(核参与时刻到时刻)为特征 歌唱控制)，以及X区和1Man区(歌唱所必需的核 在歌唱过程中幼年斑雀(Taeniopygia Guttata)的学习 学习。时态层次组织的发展 我们将研究成人的运动途径。2)听觉活动将是 以相同的核为特征，允许歌曲的分布 系统听神经元与听觉选择性的发展 这只鸟自己的歌声还有待研究。慢性技术的使用将 解决了最近的一项发现，麻醉药显著改变了 歌唱系统听觉活动的分布。