CCD MOSAIC DIGITAL MAMMOGRAPHY

CCD 马赛克数字乳腺X线摄影

• 批准号: 6288046
• 负责人: Hong Liu
• 金额: $ 3.87万
• 依托单位: JOHNS HOPKINS UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1995
• 资助国家: 美国
• 起止时间: 1995-09-30 至 2000-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6288046
• 关键词: X ray; biomedical equipment development; charge coupled device camera; computer program /software; computer system design /evaluation; digital imaging; image processing; mammography; phantom model

Specific Aims and Hypotheses: The objective of this project is to develop an imaging module for full size digital x-ray mammography. We propose to explore a CCD imaging technique using a novel area-scanning, radiation- shielding mechanism. The concept uses a 6x8 mosaic of CCD imagers. These CCDs are mounted on a carrier platform with gaps between their active areas that are exactly 15 mm in width. The platform is placed under a standard mammographic unit. A lead filter is interposed between the x-ray source and the patient. The lead filter has a mosaic of CCDs and is moved in synchronism with the CCDs. To provide a complete and contiguous image the mosaic will actually be repositioned three times, and a total of four x-ray exposures is made. The unique features of the proposed technique are: large field coverage (18 cm x 24 cm), high spatial resolution (16 lp/mm to 18 lp/mm), scatter rejection and excellent contrast characteristics and lesion detectability under clinical conditions. Methods and Experiments: The proposed imaging concept is unique because its novel optical configuration and scanning-sampling method differs significantly from existing techniques. In order to test our hypotheses, we propose to build a laboratory system to measure modulation transfer function, signal-to-noise ratio, detective quantum efficiency, and lesion detectability. We also propose to conduct phantom studies. Based on our preliminary experiments, a dose efficient, x-ray quantum noise limited system will be achieved using the proposed CCD imaging module. The lesion detectability of this digital mammographic technique is comparable to the gold standard of screen-film technique under the same conditions.

具体目标和假设：这个项目的目标是发展

项目成果

Composite x-ray image assembly for large-field digital mammography with one- and two-dimensional positioning of a focal plane array.

用于大视场数字乳腺 X 线摄影的复合 X 射线图像组件，具有焦平面阵列的一维和二维定位。

• DOI: 10.1118/1.598177
• 发表时间: 1998
• 期刊: Medical physics
• 影响因子: 3.8
• 作者: Halama,G;McAdoo,J;Liu,H
• 通讯作者: Liu,H

Signal-to-noise ratio and detective quantum efficiency analysis of optically coupled CCD mammography imaging systems.

光耦合 CCD 乳腺 X 线摄影成像系统的信噪比和检测量子效率分析。

• DOI: 10.1016/s1076-6332(96)80269-8
• 发表时间: 1996
• 期刊: Academic radiology
• 影响因子: 4.8
• 作者: Liu,H;Fajardo,LL;Penny,BC
• 通讯作者: Penny,BC

Comparison of contrast detail curves of full field digital with screen film breast phantom images.

全场数字与屏幕胶片乳房幻像图像的对比度细节曲线比较。

• DOI: 10.2741/a108
• 发表时间: 1996
• 期刊: Frontiers in bioscience : a journal and virtual library
• 作者: Visweswaran,A;Liu,H;Fajardo,LL;DeAngelis,GA
• 通讯作者: DeAngelis,GA

Interpolation algorithms for digital mammography systems with multiple detectors.

• DOI: 10.1016/s1076-6332(99)80403-6
• 发表时间: 1999-03
• 期刊: Academic radiology
• 影响因子: 4.8
• 作者: Hong Liu;Ge Wang;Jinghong Chen;Laurie L. Fajardo