ARGATROBAN ACUTE MYOCARDIAL INFRACTION STUDY
ARGATROBAN ACUTE MYOCARDIAL INFRACTION STUDY
ARGATROBAN 急性心肌梗死研究
批准号：
6246603
负责人：
MALVIN D CHEITLIN
金额：
$3.14万
依托单位国家：
美国
项目类别：
财政年份：
1997
资助国家：
美国
项目状态：
已结题
起止时间：
1997-03-03 至 1997-11-30
关键词：
acute disease /disorder antithrombins clinical research clinical trials congestive heart failure coronary artery coronary bypass dosage drug screening /evaluation human mortality human subject human therapy evaluation intraluminal angioplasty myocardial infarction myocardial ischemia /hypoxia outcomes research relapse /recurrence streptokinase
中文摘要
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英文摘要
The primary objective of this study is to evaluate and compare acute MI
patients receiving the thrombolytic streptokinase and either high or low
dose of the thrombin inhibitor, Argatroban in accelerating the lysis of
coronary artery clots. The end points are: death, recurrent MI,
angioplasty, coronary artery bypass grafting, new onset congestive heart
failure and recurrent ischemia. The GCRC will act in the capacity of an
Runblind investigatorS and mix unblinded IV study drug, monitor the PTT
and make adjustments in study drug dose as delineated in the protocol.
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