SABRIL VS CARBAMAZEPINE MONOTHERAPY IN NONREFRACTORY COMPLEX PARTIAL SEIZURES

SABRIL 与卡马西平单一疗法治疗非难治性复杂性部分性癫痫发作

• 批准号: 6246847
• 负责人: KATHERINE HENRY
• 金额: $ 2.39万
• 依托单位: NEW YORK UNIVERSITY SCHOOL OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-02-12 至 1997-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6246847
• 关键词: anticonvulsants; brain disorder chemotherapy; carbamazepine; clinical research; clinical trials; combination chemotherapy; drug screening /evaluation; human subject; human therapy evaluation; partial seizure

This multicenter, randomized, double-blind, placebo-controlled trial will determine the efficacy of Sabril (vigabatrin) as add-on therapy in non- refractory patients who experience occasional complex partial seizures while on carbamazepine monotherapy. The efficacy, safety and impact on quality of life of rational polytherapy with Sabril and carbamazepine.

这项多中心、随机、双盲、安慰剂对照试验将 确定Sabril（氨己烯酸）作为非- 偶尔出现复杂部分性癫痫发作的难治性患者 而卡马西平单药治疗。 有效性、安全性和影响 合理应用喜保宁和卡马西平综合治疗的生活质量。