BEST DECISION

最佳决定

• 批准号: 2011452
• 负责人: DAVID G. DOEPEL
• 金额: $ 10万
• 依托单位: ECHO BRIDGE PRODUCTIONS, INC.
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-09-30 至 1998-09-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2011452
• 关键词: DVD /CD ROM; behavioral /social science research tag; brca gene; breast neoplasms; cancer risk; clinical research; computer assisted medical decision making; computer human interaction; computer program /software; computer system design /evaluation; data collection methodology /evaluation; genetic counseling; genetic disorder diagnosis; human subject; interactive multimedia; neoplasm /cancer education

This proposal requests funds to develop an innovative interactive CD- ROM, "Best Decision", for individuals to use when deciding whether or not to undergo genetic testing for inherited susceptibility to breast cancer. Available through primary care, mammography, oncology, genetics counseling, and other health care settings, "Best Decision" will be appropriate for in-office and in-home use, which location is most suitable to the consumer and provides a private room with a computer with CD-ROM capability. As a tool to aid in decision making, "Best Decision" will present standardized information and resource material to educate women regarding 1) their personal risk of developing breast cancer whether due to inherited pre-disposition or some other factor; 2) the suitability of BRCA1 testing, its risks and benefits; and 3) decision-making options and strategies, and the associated risks and benefits of decision choices. PROPOSED COMMERCIAL APPLICATION: The CD-ROM will be marketed to clinical genetics research sites, mammography centers, HMOs, hospitals, community health centers. It also can be customized to include the established genetics counseling protocols of an organization, thereby increasing its marketability to HMOs which can provide it as a value-added service.

该提案要求提供资金来开发创新的交互式 CD- ROM，“最佳决策”，供个人在决定是否或 不接受乳腺癌遗传易感性基因检测 癌症。 通过初级保健、乳房X光检查、肿瘤学、 遗传咨询和其他医疗保健机构，“最佳决策” 适合办公室和家庭使用，其位置是 最适合消费者并提供私人房间 具有 CD-ROM 功能的计算机。 作为辅助决策的工具， 《最佳决策》将呈现标准化的信息和资源 向妇女提供有关 1) 个人风险的教育材料 罹患乳腺癌，无论是由于遗传倾向还是 其他一些因素； 2) BRCA1检测的适用性、风险和 好处; 3) 决策选择和策略，以及 决策选择的相关风险和收益。 拟议的商业应用：该 CD-ROM 将销售给 临床遗传学研究中心、乳房X光检查中心、HMO、 医院、社区卫生服务中心。还可以定制为 包括已建立的遗传咨询方案 组织，从而提高其对 HMO 的适销性，这可以 将其作为增值服务提供。