PREPARATION OF ANTI-AIDS BULK DRUGS AND CHEMICALS

该项目用于制备已知的化学品和原料药 这是该计划所需要的毒理学，药理学和临床 使用. 选择用于制备的化合物不容易获得， 从原始供应商处或在 公开市场 该项目是DTP计划的一部分， 用于治疗艾滋病的化学品和药物。 该项目提供了获得几乎任何类型的化学品的手段 化合物和提供大量或非常高纯度的能力 毒品 准备材料的数量将由 药物资源分支。 许多准备工作将涉及一个 各种各样的化学结构。 许多准备工作将 涉及多个步骤的顺序，所有准备的材料将完全 表征了 溶解度和稳定性研究以及成本数据将在 应要求提供。

The project is for the preparation of known chemicals and bulk drugs which are needed by the Program for toxicology, pharmacology and clinical use. The compounds selected for preparation are not readily available in the quality or quantities required from the original supplier or on the open market. This project is part of the DTP's program to procure bulk chemicals and drugs for the treatment of AIDS. This project provides the means to obtain nearly any type of chemical compound and the ability to provide large quantities or very high purity drugs. Assignments of materials for preparation will originate with the Pharmaceutical Resources Branch. Many of the preparations will involve a wide variety of chemical structures. Many of the preparations will involve multi-step sequences and all materials prepared will be fully characterized. Solubility and stability studies and cost data will be provided upon request.