Does disconnection in the aging brain cause age-related movement decline?

衰老的大脑断线是否会导致与年龄相关的运动能力下降？

• 批准号: DE190100694
• 负责人: A/Prof Ann-Maree Vallence
• 金额: $ 26.13万
• 依托单位: Murdoch University
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Early Career Researcher Award
• 财政年份: 2019
• 资助国家: 澳大利亚
• 起止时间: 2019-01-01 至 2024-04-30
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DE190100694
• 关键词: Does; disconnection; aging; brain; cause

This project aims to use new neurophysiological approaches to understand the causal role of age-related changes in brain network connectivity to the movement control. Brain regions interact through complex and dynamic neural networks to control voluntary movement, but whether age-related changes in network connectivity drive age-related decline in movement control is unknown. This project will provide significant benefits such as the neurophysiological knowledge required to develop targeted interventions to improve movement control in the aging population.

该项目旨在使用新的神经生理学方法来了解与年龄相关的大脑网络连接变化对运动控制的因果作用。大脑区域通过复杂而动态的神经网络相互作用来控制自主运动，但网络连接的年龄相关变化是否会导致运动控制能力的年龄相关下降尚不清楚。该项目将提供显着的好处，如神经生理学知识，需要制定有针对性的干预措施，以改善老年人口的运动控制。