CONTINUOUS UREA MONITOR

连续尿素监测仪

• 批准号: 2645481
• 负责人: WARREN C CLAY
• 金额: $ 10万
• 依托单位: NORFOLK ENGINEERING
• 依托单位国家: 美国
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-05-01 至 1999-01-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2645481
• 关键词: artificial membranes; biomaterial development /preparation; biomedical equipment development; blood chemistry; electrochemistry; electrodes; fluid flow; hemodialysis; patient monitoring device; titanium; urea

An electrochemical sensor will be used to continuously monitor urea during hemodialysis. The sensor can be operated on the blood side or on the solution side. Detection is on a plated metal electrode and is a direct measure of the quantity of urea present. A membrane is provided to protect the sensor from blood. Additional measures are required to limit the response to urea only. PROPOSED COMMERCIAL APPLICATION The device will be used to permit direct monitoring of urea levels in the blood, the dialysis fluid effluent, or both during hemodialysis. There are over 200,000 dialysis patients in the United States receiving multiple treatments per week. Even limited penetration by this device represents a large market.

电化学传感器将用于连续监测尿素 在血液透析期间。 传感器可以在血液侧操作， 在解决方案方面。 检测是在镀金属电极上进行的， 直接测量存在的尿素的量。 膜被 用于保护传感器免受血液影响。 额外措施 要求仅限制对尿素的反应。 建议的商业应用 该装置将用于直接监测尿素水平， 血液、透析液流出物或两者。 在美国有超过20万的透析病人 每周多次治疗。 即使是有限的穿透力 代表着一个巨大的市场。