VIDEOTAPE FOR RECRUITMENT TO ONCOLOGY CLINICAL TRIALS

临床试验的患者增加是一个难题。已经 据估计， 成年人代表了潜在的患者数量的一小部分（<10%）， available.据进一步估计， 试验累积了1%到1.5%的潜在可用患者。三大 NCI支持的研究的平均发生率分别为32%、113%和119% 比计划的速度慢。该SBlR的目的是 开发并评估招募癌症患者的录像带 临床试验录像带的具体目的是：（1）增加 招募癌症临床试验患者;（2）增加 患者对其参与的理解和满意度 临床试验;和（3）提供一个具有成本效益的，标准化的 临床试验的招募策略。这些目标将会实现 通过录像带的发展。这盘录像带将作为 描述临床试验和解决患者 对参与的担忧和担忧。在拟议的第一阶段， SBlR我们将确定录像带的内容需求， 有效的呈现方式。在第二阶段，录像带将 制作和评价。SBIR的最终产品将是一盘录像带 可以用于临床试验的招募。虽然拟议的 录像带将在乳腺癌的背景下开发和测试 临床试验，开发的方法将转移到其他 临床试验

Patient accrual to clinical trials is a difficult problem. It has been estimated that total accrual to NCI-supported cancer treatment trials in adults represents a fraction (<10%) of the number of patients potentially available. It has been further estimated that Cooperative Group adjuvant trials accrue 1% to 1.5% of potentially available patients. Three major NCI supported studies had average rates that were 32%, 113%, and 119% slower than planned projection rates. The purpose of this SBlR is to develop and evaluate a videotape for recruiting patients to cancer clinical trials. The Specific Aims of the videotape are: (1) To increase recruitment of patients to cancer clinical trials; (2) To increase patient's understanding of and satisfaction with their participation in clinical trials; and (3) To provide a cost-effective, standardized recruitment strategy for clinical trials. These aims will be accomplished through the development of a videotape. This videotape will serve as an educational tool to describe clinical trials and to address patient's fears and concerns regarding participation. During Phase I of the proposed SBlR we will determine the content needs of the videotape and the most effective presentation method. During Phase II, the videotape will be produced and evaluated. The end product of this SBIR will be a videotape that can be used for recruitment to clinical trials. While the proposed videotape will be developed and tested in the context of breast cancer clinical trials, the method developed will be transferable to other clinical trials.