NIH CAREER DEVELOPMENT AWARD

美国国立卫生研究院职业发展奖

• 批准号: 2685215
• 负责人: Ichiro Kawachi
• 金额: $ 6.91万
• 依托单位: HARVARD MEDICAL SCHOOL
• 依托单位国家: 美国
• 财政年份: 1996
• 资助国家: 美国
• 起止时间: 1996-04-01 至 2001-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2685215
• 关键词: behavioral /social science research tag; cardiovascular disorder epidemiology; clinical research; coronary disorder; disease /disorder proneness /risk; human data; human middle age (35-64); human old age (65+); occupational health /safety; occupational psychology; occupational stressor; psychological stressor; questionnaires; social support network; socioenvironment; work site

The aim of this proposal is to enable the candidate, Dr. Ichiro Kawachi, M.D., Ph.D., to develop his research career in cardiovascular epidemiology with a special emphasis on psychosocial risk factors. This proposal describes a 5-year program of research that will examine prospectively, in men and women, major psychosocial risk factors for coronary heart disease (CHD). The hypotheses to be examined include: the influence of psychosocial work environment (job strain and shift work) on CHD risk; the relationship of psychological stress (in particular, phobic anxiety) to CHD risk; and the role of resistance resources (social networks and support in the work-place and at home) in moderating the association between psychosocial stressors and CHD risk. The investigations will be performed in two cohort studies with established track records of research in cardiovascular disease etiology: the Nurses' Health Study, consisting of 121,700 women aged 49 to 74 years; and the Health Professionals Followup Study, consisting of 51,529 men aged 48 to 83 years. The proposed research will be instrumental in establishing Dr. Kawachi's career as a researcher at the forefront of psychosocial research in cardiovascular disease. In addition, the research promises to advance the field in several important ways, including bringing a very large prospective cohort of women to a research area that has been dominated by data in men. If awarded the RCDA, Dr. Kawachi's immediate career plan is to refine the psychosocial components of the two ongoing cohort studies, and to initiate a series of investigations that will elucidate the major psychosocial determinants of cardiovascular disease. In the long term, Dr. Kawachi's career plan is to build on his successful collaborations with investigators in other disciplines - including physiology, psychology, and sociology - to develop a comprehensive program of cardiovascular research with an emphasis on prevention.

该提案的目的是让候选人 Ichiro Kawachi 博士， 医学博士、博士，发展心血管研究事业 流行病学，特别强调社会心理危险因素。这 提案描述了一项为期 5 年的研究计划，该计划将审查 前瞻性地，在男性和女性中，主要的心理社会风险因素 冠心病（CHD）。要检验的假设包括： 心理社会工作环境的影响（工作压力和轮班工作） 关于冠心病风险；心理压力的关系（特别是， 恐惧性焦虑）增加冠心病风险；以及抵抗资源（社会 工作场所和家庭中的网络和支持）来调节 心理社会压力源与冠心病风险之间的关联。这 调查将在两项队列研究中进行，已确定 心血管疾病病因学研究跟踪记录：护士的 健康研究，由 121,700 名 49 至 74 岁女性组成；和 健康专业人员跟踪研究，由 51,529 名年龄在 48 岁至 83年。拟议的研究将有助于建立博士。 河内作为心理学前沿研究员的职业生涯 心血管疾病研究。此外，研究还承诺 以几个重要的方式推进该领域的发展，包括带来非常 大量前瞻性女性群体进入一个已被 以男性数据为主。 如果获得 RCDA，河内博士的近期职业计划是完善 两项正在进行的队列研究的心理社会成分，以及 启动一系列调查，以阐明主要问题 心血管疾病的社会心理决定因素。从长远来看， 河内博士的职业规划是建立在他成功合作的基础上 与其他学科的研究人员 - 包括生理学， 心理学和社会学 - 制定一个全面的计划 心血管研究，重点是预防。