POG9470--CI 980 IN CHILDREN WITH SOLID TUMORS

POG9470--CI 980 用于患有实体瘤的儿童

• 批准号: 6279171
• 负责人: FAITH H KUNG
• 金额: $ 1.43万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN DIEGO
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-12-01 至 1998-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6279171
• 关键词: antineoplastics; child (0-11); clinical research; drug adverse effect; human subject; human therapy evaluation; neoplasm /cancer chemotherapy; neoplasm /cancer pharmacology; pediatric neoplasm /cancer; pediatric pharmacology; pharmacokinetics

POG 9470 to determine the acute and chronic dose-limiting toxicities and time to recovery, determine if there is cumulative toxicity when multiple courses of drug are given and correlate the pharmacokinetic data with toxicity.

POG 9470测定急性和慢性剂量限制性毒性， 恢复时间，确定当多次给药时是否存在累积毒性 给药疗程，并将药代动力学数据与 毒性