INNATE IMMUNITY

纽约医学院150多年来一直致力于 通过教育、研究和宣传提高公众的健康。 每年，科学院都会主办一次基础科学研讨会，探讨 综合开发领域。选择这种方法是为了 允许研究人员之间最大限度地互动，并提高创造力 通过确定需要解决的新问题和新方法 去寻找问题的答案。 在哺乳动物免疫学家中，最近出现了一种范式的转变。 与此同时，人们认识到免疫的许多特异性 对病原体的反应是由先天免疫反应识别引导的 机械装置。与此同时，最近的分子证据表明 先天免疫反应机制在进化中是保守的。结果, 似乎可以在低等生物中进行的基因实验 很可能为哺乳动物的免疫反应提供新的见解。这 这次会议是将来自世界各地的科学家聚集在一起的首次尝试 非常不同的哺乳动物免疫生物学背景，果蝇 遗传学和植物抗病性来讨论这一新兴领域。 为期一天半的研讨会将于一九九八年十二月七日至八日举行： 《与生俱来的免疫：古老的信号，现代的含义》试图带来 来自互补背景的科学家共同解决这一新问题 菲尔德在一群科学家和临床医生面前 基础免疫学。演讲主题包括：哺乳动物先天免疫 反应，先天免疫和适应性免疫之间的联系，先天免疫和 危险、昆虫和植物免疫反应、REL蛋白的识别 以及先天免疫反应的多样性。

The New York Academy of Medicine has been dedicated for over 150 years to enhancing the health of public through education, research and advocacy. Each year the Academy sponsors a Basic Science Symposium which explores a developing field in a comprehensive manner. This approach is chosen to allow maximal interaction among researchers and to enhance the creativity of the field by identify new problems to be addressed and new approaches to seeking answers to the problems. Among mammalian immunologists, there has been a recent shift in paradigms accompanying the recognition that much of the specificity of the immune response for pathogens is guided by innate immune response recognition mechanisms. At the same time, recent molecular evidence suggests that innate immune response mechanisms are conserved in evolution. As a result, it seems that genetic experiments that can be conducted in lower organisms are likely to provide new insights into mammalian immune responses. This meeting represents the first attempt to bring together scientists from the very different backgrounds of mammalian immunobiology, Drosophila genetics, and plant disease resistance to discuss this emerging field. This one and one-half day symposium to be held on December 7-8, 1998: "Innate Immunity: Ancient Signals, Modern Implications" seeks to bring scientists from complementary backgrounds together to address this new field before an audience of scientists and clinicians with interest in basic immunology. Topics to be presented include: Mammalian Innate Immune Responses, Links Between Innate and Adaptive Immunity, Innate Immunity and the Recognition of Danger, Insect and Plant Immune Responses, Rel Proteins and the Diversity of Innate Immune Responses.